The invasive pathogen Yersinia pestis disrupts host blood vasculature to spread and provoke hemorrhages

Yersinia pestis is a powerful pathogen with a rare invasive capacity. After a flea bite, the plague bacillus can reach the bloodstream in a matter of days giving way to invade the whole organism reaching all organs and provoking disseminated hemorrhages. However, the mechanisms used by this bacteriu...

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Veröffentlicht in:	PLoS neglected tropical diseases 2021-10, Vol.15 (10), p.e0009832-e0009832
Hauptverfasser:	Mikaty, Guillain, Coullon, Héloïse, Fiette, Laurence, Pizarro-Cerdá, Javier, Carniel, Elisabeth
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal genetics Animals Bacteria Bacteriology Biology and Life Sciences Blood Blood vessels Blood Vessels - microbiology Body organs Cell Behavior Cellular Biology Circulatory system Complications and side effects Development and progression Drainage systems Experiments Genes Genetics Haemorrhage Hemorrhage Hemorrhage - etiology Hemorrhage - microbiology Host-bacteria relationships Human health and pathology Humans Immune system In vivo methods and tests Infections Infectious diseases Invasiveness Laboratories Life Sciences Lymph Lymph nodes Lymphatic system Medicine and Health Sciences Mice Microbiology and Parasitology Organs Pathogenesis Pathogens Permeability Phenotypes Physiological aspects Plague Plague - complications Plague - microbiology Plasmids Plasmids - genetics Plasmids - metabolism Porosity Research and Analysis Methods Secretion Tropical diseases Vascular system Virulence Yersinia infections Yersinia pestis Yersinia pestis - genetics Yersinia pestis - physiology
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