Structure-guided antibody cocktail for prevention and treatment of COVID-19

Development of effective therapeutics for mitigating the COVID-19 pandemic is a pressing global need. Neutralizing antibodies are known to be effective antivirals, as they can be rapidly deployed to prevent disease progression and can accelerate patient recovery without the need for fully developed...

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Veröffentlicht in:	PLoS pathogens 2021-10, Vol.17 (10), p.e1009704-e1009704
Hauptverfasser:	Su, Shih-Chieh, Yang, Tzu-Jing, Yu, Pei-Yu, Liang, Kang-Hao, Chen, Wan-Yu, Yang, Chun-Wei, Lin, Hsiu-Ting, Wang, Mei-Jung, Lu, Ruei-Min, Tso, Hsien-Cheng, Chung, Meng-Jhe, Hsieh, Tzung-Yang, Chang, Yu-Ling, Lin, Shin-Chang, Hsu, Fang-Yu, Ke, Feng-Yi, Wu, Yi-Hsuan, Hwang, Yu-Chyi, Liu, I-Ju, Liang, Jian-Jong, Liao, Chun-Che, Ko, Hui-Ying, Sun, Cheng-Pu, Wu, Ping-Yi, Jan, Jia-Tsrong, Chang, Yuan-Chih, Lin, Yi-Ling, Tao, Mi-Hua, Hsu, Shang-Te Danny, Wu, Han-Chung
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Antibodies Antiviral agents Biology and life sciences Cloning Composition Coronaviruses COVID-19 Disease control Disease resistance Drug development Drug resistance Electron microscopy Epitopes Health aspects Immunological research Immunotherapy Infections Medicine and health sciences Middle East respiratory syndrome Monoclonal antibodies Neutralization Pandemics Prevention Proteins Research and Analysis Methods Respiratory diseases Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Spike protein Viral antibodies Viral diseases Viral proteins
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