Targeted proteomics as a tool to detect SARS-CoV-2 proteins in clinical specimens

The rapid, sensitive and specific detection of SARS-CoV-2 is critical in responding to the current COVID-19 outbreak. In this proof-of-concept study, we explored the potential of targeted mass spectrometry (MS) based proteomics for the detection of SARS-CoV-2 proteins in both research samples and cl...

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Veröffentlicht in:	PloS one 2021-11, Vol.16 (11), p.e0259165-e0259165
Hauptverfasser:	Bezstarosti, Karel, Lamers, Mart M, Doff, Wouter A. S, Wever, Peter C, Thai, Khoa T. D, van Kampen, Jeroen J. A, Haagmans, Bart L, Demmers, Jeroen A. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and life sciences Coronaviruses COVID-19 Evaluation Mass spectrometry Mass spectroscopy Medical tests Medicine and health sciences Methods Nucleocapsids Patients Peptides Physical Sciences Proteins Proteomics Research and Analysis Methods Scientific imaging Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Software Sputum Tryptic peptides Viral diseases Viral infections Viruses
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