Effectiveness of seasonal malaria chemoprevention (SMC) treatments when SMC is implemented at scale: Case-control studies in 5 countries

Seasonal malaria chemoprevention (SMC) has shown high protective efficacy against clinical malaria and severe malaria in a series of clinical trials. We evaluated the effectiveness of SMC treatments against clinical malaria when delivered at scale through national malaria control programmes in 2015...

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Veröffentlicht in:	PLoS medicine 2021-09, Vol.18 (9), p.e1003727-e1003727
Hauptverfasser:	Cairns, Matthew, Ceesay, Serign Jawo, Sagara, Issaka, Zongo, Issaka, Kessely, Hamit, Gamougam, Kadidja, Diallo, Abdoulaye, Ogboi, Johnbull Sonny, Moroso, Diego, Van Hulle, Suzanne, Eloike, Tony, Snell, Paul, Scott, Susana, Merle, Corinne, Bojang, Kalifa, Ouedraogo, Jean Bosco, Dicko, Alassane, Ndiaye, Jean-Louis, Milligan, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa, Western - epidemiology Age Factors Amodiaquine - adverse effects Amodiaquine - therapeutic use Antimalarials - adverse effects Antimalarials - therapeutic use Biology and Life Sciences Caregivers Case-Control Studies Child, Preschool Children & youth Clinical trials Communicable Disease Control Drug Combinations Drug therapy Female Fever Health facilities Households Humans Incidence Infant Infections Malaria Malaria, Falciparum - diagnosis Malaria, Falciparum - epidemiology Malaria, Falciparum - parasitology Malaria, Falciparum - prevention & control Male Medicine and Health Sciences Neighborhoods Parasite Load Parasites People and Places Plasmodium falciparum - drug effects Plasmodium falciparum - growth & development Prevention Principal components analysis Program Evaluation Public health Pyrimethamine - adverse effects Pyrimethamine - therapeutic use Risk Assessment Risk Factors Seasonal variations (Diseases) Seasons Statistics Sulfadoxine - adverse effects Sulfadoxine - therapeutic use Time Factors Treatment Outcome
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