T cell derived HIV-1 is present in the CSF in the face of suppressive antiretroviral therapy

HIV cerebrospinal fluid (CSF) escape, where HIV is suppressed in blood but detectable in CSF, occurs when HIV persists in the CNS despite antiretroviral therapy (ART). To determine the virus producing cell type and whether lowered CSF ART levels are responsible for CSF escape, we collected blood and...

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Veröffentlicht in:PLoS pathogens 2021-09, Vol.17 (9), p.e1009871-e1009871
Hauptverfasser: Lustig, Gila, Cele, Sandile, Karim, Farina, Derache, Anne, Ngoepe, Abigail, Khan, Khadija, Gosnell, Bernadett I, Moosa, Mahomed-Yunus S, Ntshuba, Ntombi, Marais, Suzaan, Jeena, Prakash M, Govender, Katya, Adamson, John, Kløverpris, Henrik, Gupta, Ravindra K, Harrichandparsad, Rohen, Patel, Vinod B, Sigal, Alex
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Sprache:eng
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