Attenuated infection by a Pteropine orthoreovirus isolated from an Egyptian fruit bat in Zambia

Pteropine orthoreovirus (PRV) is an emerging bat-borne zoonotic virus that causes severe respiratory illness in humans. Although PRVs have been identified in fruit bats and humans in Australia and Asia, little is known about the prevalence of PRV infection in Africa. Therefore, this study performed...

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Veröffentlicht in:	PLoS neglected tropical diseases 2021-09, Vol.15 (9), p.e0009768-e0009768
Hauptverfasser:	Harima, Hayato, Sasaki, Michihito, Orba, Yasuko, Okuya, Kosuke, Qiu, Yongjin, Wastika, Christida E, Changula, Katendi, Kajihara, Masahiro, Simulundu, Edgar, Yamaguchi, Tomoyuki, Eto, Yoshiki, Mori-Kajihara, Akina, Sato, Akihiko, Taniguchi, Satoshi, Takada, Ayato, Saijo, Masayuki, Hang'ombe, Bernard M, Sawa, Hirofumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Animals Animals as carriers of disease Antibodies Bats Biology and Life Sciences Causes of Chiroptera Chiroptera - virology Chlorocebus aethiops Colon Colour Epidemiology Fruits Genetic analysis Genomes Health aspects Identification and classification Illnesses Infections Medicine and Health Sciences Mice Mice, Inbred BALB C Microbiological strains National parks Neutralization Next-generation sequencing Nucleotide sequence Orthoreovirus - isolation & purification Pathogenicity Pathogens Patients PCR People and Places Phylogeny Polymerase chain reaction Public health Reoviridae Infections - epidemiology Reoviridae Infections - veterinary Reoviridae Infections - virology Reoviruses Research and Analysis Methods Respiratory diseases Respiratory disorders Risk factors RNA polymerase RNA virus infections Serum Statistics Strain Strain analysis Straw Tourism Tropical diseases Vero Cells Viruses Zambia - epidemiology Zoonoses
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