Intracluster correlation coefficients in a large cluster randomized vaccine trial in schools: Transmission and impact of shared characteristics

Cluster randomized trials (cRCT) to assess vaccine effectiveness incorporate indirect effects of vaccination, helping to inform vaccination policy. To calculate the sample size for a cRCT, an estimate of the intracluster correlation coefficient (ICC) is required. For infectious diseases, shared char...

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Veröffentlicht in:	PloS one 2021-10, Vol.16 (10), p.e0254330-e0254330
Hauptverfasser:	Whelan, Jane, Marshall, Helen, Sullivan, Thomas R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjustment Biology and Life Sciences Clinical trials Clustering Correlation Correlation coefficient Correlation coefficients Earth Sciences Estimates Ethnicity Evaluation Health care networks Health risks Immunization Infections Infectious diseases Marshall, Thomas Mathematical analysis Medicine and Health Sciences Metropolitan areas People and Places Public health Questionnaires R&D Research & development Research and Analysis Methods Risk analysis Risk factors Rural areas Schools Severe acute respiratory syndrome coronavirus 2 Size estimation Social behavior Social interactions Social Sciences Students Teenagers Vaccination Vaccine efficacy Vaccines Whelan, Helen Womens health
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