Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya
Successful scale-up of PrEP for HIV prevention in African adolescent girls and young women (AGYW) requires integration of PrEP into young women's everyday lives. We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and r...
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| creator | Rousseau, Elzette Katz, Ariana W K O'Rourke, Shannon Bekker, Linda-Gail Delany-Moretlwe, Sinead Bukusi, Elizabeth Travill, Danielle Omollo, Victor Morton, Jennifer F O'Malley, Gabrielle Haberer, Jessica E Heffron, Renee Johnson, Rachel Celum, Connie Baeten, Jared M van der Straten, Ariane |
| description | Successful scale-up of PrEP for HIV prevention in African adolescent girls and young women (AGYW) requires integration of PrEP into young women's everyday lives. We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and relational enablers and disablers were explored at key moments during their PrEP-user journey from awareness, initiation and early use through persistence, including PrEP pauses, restarts, and discontinuation. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community. Daily pill-taking was challenging for AGYW due to individual, relational and structural factors and PrEP interruptions (intended or unintended) were described as part of AGYW's PrEP-user journey. Disclosure, social support, adolescent-friendly health counseling, and convenient access to PrEP were reported as key enablers for PrEP persistence. |
| doi_str_mv | 10.1371/journal.pone.0258542 |
| format | Article |
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We conducted interviews and focus group discussions with 137 AGYW PrEP users aged 16-25 from South Africa and Kenya. Individual and relational enablers and disablers were explored at key moments during their PrEP-user journey from awareness, initiation and early use through persistence, including PrEP pauses, restarts, and discontinuation. PrEP uptake was facilitated when offered as part of an integrated sexual reproductive health service, but hampered by low awareness, stigma and misconceptions about PrEP in the community. Daily pill-taking was challenging for AGYW due to individual, relational and structural factors and PrEP interruptions (intended or unintended) were described as part of AGYW's PrEP-user journey. 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This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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| recordid | cdi_plos_journals_2582105152 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central; Free Full-Text Journals in Chemistry; Sociological Abstracts; Public Library of Science (PLoS) |
| subjects | Acquired immune deficiency syndrome Adolescent Adolescent girls Adolescents AIDS Anti-HIV Agents - administration & dosage Biology and Life Sciences Counseling Data collection Disclosure Disease prevention Domestic violence Female Girls Health aspects Health risks Health services HIV HIV Infections - prevention & control HIV Infections - psychology Human immunodeficiency virus Humans Implementation Implementation Science Kenya Medical research Medicine and Health Sciences Pre-Exposure Prophylaxis Prevention Psychology, Adolescent Qualitative research Reproductive health Self disclosure Sexual behavior Sexual health Sexually transmitted diseases Social interactions Social Sciences Social Stigma Social Support South Africa STD Teenage girls Teenagers Tutu, Desmond Women Women - psychology Young Adult Young adults Young women |
| title | Adolescent girls and young women's PrEP-user journey during an implementation science study in South Africa and Kenya |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T14%3A51%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adolescent%20girls%20and%20young%20women's%20PrEP-user%20journey%20during%20an%20implementation%20science%20study%20in%20South%20Africa%20and%20Kenya&rft.jtitle=PloS%20one&rft.au=Rousseau,%20Elzette&rft.date=2021-10-14&rft.volume=16&rft.issue=10&rft.spage=e0258542&rft.epage=e0258542&rft.pages=e0258542-e0258542&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0258542&rft_dat=%3Cgale_plos_%3EA678973837%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2582105152&rft_id=info:pmid/34648589&rft_galeid=A678973837&rft_doaj_id=oai_doaj_org_article_cbadd27d13d9478da1837897139170a9&rfr_iscdi=true |