Non-clinical assessment of lubrication and free radical scavenging of an innovative non-animal carboxymethyl chitosan biomaterial for viscosupplementation: An in-vitro and ex-vivo study

Lubrication and free radical scavenging are key features of biomaterials used for viscosupplementation (VS) of joints affected by osteoarthritis (OA). The objective of this study was to describe the non-clinical performance characterization of KiOmedine.sup.® CM-Chitosan, a non-animal carboxymethyl...

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Veröffentlicht in:	PloS one 2021-10, Vol.16 (10), p.e0256770-e0256770
Hauptverfasser:	Vandeweerd, Jean-Michel, Innocenti, Bernado, Rocasalbas, Guillem, Gautier, Sandrine Emilia, Douette, Pierre, Hermitte, Laurence, Hontoir, Fanny, Chausson, Mickael
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antioxidants Arthritis Biological products Biology and Life Sciences Biomaterials Biomechanics Biomedical materials Care and treatment Cartilage Chitin Chitosan Coefficient of friction Crosslinking Engineering and Technology Evaluation Free radicals Friction Hyaluronic acid Injection Injury prevention Knee Life sciences Lubrication Mechanical properties Medicine and Health Sciences Mobility Osteoarthritis Pain Physical Sciences Physiology R&D Recovery Research & development Rheology Scavenging Sheep Tribology Viscoelasticity Vitamin E
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