Renalase is a novel tissue and serological biomarker in pancreatic ductal adenocarcinoma

Dysregulated expression of the secretory protein renalase can promote pancreatic ductal adenocarcinoma (PDAC) growth in animal models. We characterized renalase expression in premalignant and malignant PDAC tissue and investigated whether plasma renalase levels corresponded to clinical PDAC characte...

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Veröffentlicht in:	PloS one 2021-09, Vol.16 (9), p.e0250539
Hauptverfasser:	Gao, Yasheen, Wang, Melinda, Guo, Xiaojia, Hu, Joanna, Chen, Tian-Min, Finn, Sade M B, Lacy, Jill, Kunstman, John W, Cha, Charles H, Bellin, Melena D, Robert, Marie E, Desir, Gary V, Gorelick, Fred S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acids Adenocarcinoma Adult Aged Aged, 80 and over Analysis Animal growth Animal models Antibodies Antigens Biological markers Biology and Life Sciences Biomarkers Biomarkers, Tumor - blood Cancer Carcinoma, Pancreatic Ductal - blood Carcinoma, Pancreatic Ductal - mortality Carcinoma, Pancreatic Ductal - pathology Case-Control Studies Diagnosis Female Gastrointestinal cancer Gene Expression Regulation, Neoplastic Genetic aspects Histochemistry Humans Immunohistochemistry Kidney cancer Labeling Laboratories Lesions Male Medical prognosis Medicine Medicine and Health Sciences Middle Aged Monoamine Oxidase - blood Neoplasm Grading Pancreas Pancreatic cancer Pancreatic Neoplasms - blood Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatitis Parametric analysis Patients Plasma Precursors Prognosis Prospective Studies Retrospective Studies Surgery Survival Survival Analysis Tissues Trauma Tumors Up-Regulation Veterans Young Adult
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