Tumor growth rate during re-challenge chemotherapy with previously used agents as salvage treatment for metastatic colorectal cancer: A retrospective study

In clinical practice, the same chemotherapeutic agents are occasionally reused (re-challenge) after failure of all available standard chemotherapy options for metastatic colorectal cancer (mCRC). However, the benefits of re-challenge chemotherapy (Re-Cx) are unclear. This retrospective study evaluat...

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Veröffentlicht in:	PloS one 2021-09, Vol.16 (9), p.e0257551
Hauptverfasser:	Ishikawa, Masashi, Takashima, Atsuo, Nagata, Yusuke, Sawada, Ryoichi, Aoki, Masahiko, Imazeki, Hiroshi, Hirano, Hidekazu, Shoji, Hirokazu, Honma, Yoshitaka, Iwasa, Satoru, Okita, Natsuko, Kato, Ken, Saruta, Masayuki, Boku, Narikazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents - therapeutic use Cancer Cancer therapies Care and treatment Chemotherapy Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Complications and side effects Disease control Drug Therapy - methods Drugs Female Gastroenterology Growth Growth rate Health services Hepatology Hospitals Humans Internal medicine Irinotecan Male Medical imaging Medical prognosis Medicine Medicine and Health Sciences Metastases Metastasis Middle Aged Neoplasm Metastasis - drug therapy Oncology Oxaliplatin Patient outcomes Patients Research and Analysis Methods Retrospective Studies Shrinkage Survival Tumors
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