Challenges in interpreting cytokine data in COVID-19 affect patient care and management

Challenges in using cytokine data are limiting Coronavirus Disease 2019 (COVID-19) patient management and comparison among different disease contexts. We suggest mitigation strategies to improve the accuracy of cytokine data, as we learn from experience gained during the COVID-19 pandemic.

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Bibliographische Detailangaben
Veröffentlicht in:	PLoS biology 2021-08, Vol.19 (8), p.e3001373-e3001373
Hauptverfasser:	Wang, Stephen Y, Takahashi, Takehiro, Pine, Alexander B, Damsky, William E, Simonov, Michael, Zhang, Yanhua, Kieras, Elizabeth, Price, Christina C, King, Brett A, Siegel, Mark D, Desir, Gary V, Lee, Alfred I, Iwasaki, Akiko, Chun, Hyung J
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Biology and Life Sciences Clinical outcomes Clinical trials Computer and Information Sciences Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - immunology COVID-19 - therapy Cytokine storm Cytokines Cytokines - immunology Disease Disease control Granulocytes Health aspects Hospitalization Humans Medical laboratories Medicine and Health Sciences Mitigation Mortality Pandemics Patient Care - methods Patients Respiratory distress syndrome SARS-CoV-2 - immunology Sepsis Severe acute respiratory syndrome coronavirus 2 Social Sciences Steroids Tumor necrosis factor-TNF Viral diseases
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