Transposon debris in ciliate genomes

The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS biology 2021-08, Vol.19 (8), p.e3001354-e3001354
Hauptverfasser: Feng, Yi, Landweber, Laura F
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page e3001354
container_issue 8
container_start_page e3001354
container_title PLoS biology
container_volume 19
creator Feng, Yi
Landweber, Laura F
description The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.
doi_str_mv 10.1371/journal.pbio.3001354
format Article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2573455172</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A674186529</galeid><doaj_id>oai_doaj_org_article_b330c4b5be3a4d43bad4a3527ce7ecc4</doaj_id><sourcerecordid>A674186529</sourcerecordid><originalsourceid>FETCH-LOGICAL-c672t-aec8f4cd89b251c50bc4a0f41730945cff432281a3456d2ef9be52012dc4bec23</originalsourceid><addsrcrecordid>eNqVkt2L1DAQwIso3nn6Hwgu6IM-7JqPSZu-CMfhx8LhgZ6-hiSd1izdZC9pRf97U7eKlXtQ8pAw-c1vMmGK4jElG8or-nIXxuh1vzkYFzacEMoF3ClOqQCxrqQUd_84nxQPUtoRwljN5P3ihAMwySg_LZ5dR-3TIaTgVw2a6NLK-ZV1vdMDrjr0YY_pYXGv1X3CR_N-Vnx68_r64t368urt9uL8cm3Lig1rjVa2YBtZGyaoFcRY0KQFWnFSg7BtC5wxSTUHUTYM29qgYISyxoJBy_hZ8eToPfQhqbnBpJiocoag1URsj0QT9E4dotvr-F0F7dTPQIid0nFwtkdlOCfZKwxyDQ1woxvQXLDKYoXWQna9mquNZo-NRT9E3S-kyxvvvqgufFWSS6A1zYLnsyCGmxHToPYuWex77TGM07tLgJpLVmX06V_o7d3NVKdzA863Ide1k1SdlxVQWQpWZ2pzC5VXg3tng8fW5fgi4cUiITMDfhs6Paakth8__Af7_t_Zq89LFo6sjSGliO3vf6ZETfP860PUNM9qnmf-AxdN5MA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2573455172</pqid></control><display><type>article</type><title>Transposon debris in ciliate genomes</title><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Feng, Yi ; Landweber, Laura F</creator><creatorcontrib>Feng, Yi ; Landweber, Laura F</creatorcontrib><description>The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.</description><identifier>ISSN: 1545-7885</identifier><identifier>ISSN: 1544-9173</identifier><identifier>EISSN: 1545-7885</identifier><identifier>DOI: 10.1371/journal.pbio.3001354</identifier><identifier>PMID: 34428213</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Biology and Life Sciences ; Ciliata ; Deoxyribonucleic acid ; DNA ; DNA methylation ; Domestication ; Evolution ; Gene expression ; Genetic aspects ; Genomes ; Genomics ; Introns ; Microbiological research ; Mutation ; Permits ; Physiological aspects ; Primer ; Transposons</subject><ispartof>PLoS biology, 2021-08, Vol.19 (8), p.e3001354-e3001354</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 Feng, Landweber. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 Feng, Landweber 2021 Feng, Landweber</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c672t-aec8f4cd89b251c50bc4a0f41730945cff432281a3456d2ef9be52012dc4bec23</citedby><cites>FETCH-LOGICAL-c672t-aec8f4cd89b251c50bc4a0f41730945cff432281a3456d2ef9be52012dc4bec23</cites><orcidid>0000-0002-7030-8540</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384191/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8384191/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793</link.rule.ids></links><search><creatorcontrib>Feng, Yi</creatorcontrib><creatorcontrib>Landweber, Laura F</creatorcontrib><title>Transposon debris in ciliate genomes</title><title>PLoS biology</title><description>The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.</description><subject>Biology and Life Sciences</subject><subject>Ciliata</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA methylation</subject><subject>Domestication</subject><subject>Evolution</subject><subject>Gene expression</subject><subject>Genetic aspects</subject><subject>Genomes</subject><subject>Genomics</subject><subject>Introns</subject><subject>Microbiological research</subject><subject>Mutation</subject><subject>Permits</subject><subject>Physiological aspects</subject><subject>Primer</subject><subject>Transposons</subject><issn>1545-7885</issn><issn>1544-9173</issn><issn>1545-7885</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqVkt2L1DAQwIso3nn6Hwgu6IM-7JqPSZu-CMfhx8LhgZ6-hiSd1izdZC9pRf97U7eKlXtQ8pAw-c1vMmGK4jElG8or-nIXxuh1vzkYFzacEMoF3ClOqQCxrqQUd_84nxQPUtoRwljN5P3ihAMwySg_LZ5dR-3TIaTgVw2a6NLK-ZV1vdMDrjr0YY_pYXGv1X3CR_N-Vnx68_r64t368urt9uL8cm3Lig1rjVa2YBtZGyaoFcRY0KQFWnFSg7BtC5wxSTUHUTYM29qgYISyxoJBy_hZ8eToPfQhqbnBpJiocoag1URsj0QT9E4dotvr-F0F7dTPQIid0nFwtkdlOCfZKwxyDQ1woxvQXLDKYoXWQna9mquNZo-NRT9E3S-kyxvvvqgufFWSS6A1zYLnsyCGmxHToPYuWex77TGM07tLgJpLVmX06V_o7d3NVKdzA863Ide1k1SdlxVQWQpWZ2pzC5VXg3tng8fW5fgi4cUiITMDfhs6Paakth8__Af7_t_Zq89LFo6sjSGliO3vf6ZETfP860PUNM9qnmf-AxdN5MA</recordid><startdate>20210824</startdate><enddate>20210824</enddate><creator>Feng, Yi</creator><creator>Landweber, Laura F</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PATMY</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><scope>CZG</scope><orcidid>https://orcid.org/0000-0002-7030-8540</orcidid></search><sort><creationdate>20210824</creationdate><title>Transposon debris in ciliate genomes</title><author>Feng, Yi ; Landweber, Laura F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c672t-aec8f4cd89b251c50bc4a0f41730945cff432281a3456d2ef9be52012dc4bec23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Biology and Life Sciences</topic><topic>Ciliata</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA methylation</topic><topic>Domestication</topic><topic>Evolution</topic><topic>Gene expression</topic><topic>Genetic aspects</topic><topic>Genomes</topic><topic>Genomics</topic><topic>Introns</topic><topic>Microbiological research</topic><topic>Mutation</topic><topic>Permits</topic><topic>Physiological aspects</topic><topic>Primer</topic><topic>Transposons</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Feng, Yi</creatorcontrib><creatorcontrib>Landweber, Laura F</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Canada</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><collection>PLoS Biology</collection><jtitle>PLoS biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Feng, Yi</au><au>Landweber, Laura F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transposon debris in ciliate genomes</atitle><jtitle>PLoS biology</jtitle><date>2021-08-24</date><risdate>2021</risdate><volume>19</volume><issue>8</issue><spage>e3001354</spage><epage>e3001354</epage><pages>e3001354-e3001354</pages><issn>1545-7885</issn><issn>1544-9173</issn><eissn>1545-7885</eissn><abstract>The germline genomes of ciliated protists are replete with “junk” DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>34428213</pmid><doi>10.1371/journal.pbio.3001354</doi><orcidid>https://orcid.org/0000-0002-7030-8540</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1545-7885
ispartof PLoS biology, 2021-08, Vol.19 (8), p.e3001354-e3001354
issn 1545-7885
1544-9173
1545-7885
language eng
recordid cdi_plos_journals_2573455172
source DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central
subjects Biology and Life Sciences
Ciliata
Deoxyribonucleic acid
DNA
DNA methylation
Domestication
Evolution
Gene expression
Genetic aspects
Genomes
Genomics
Introns
Microbiological research
Mutation
Permits
Physiological aspects
Primer
Transposons
title Transposon debris in ciliate genomes
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T20%3A01%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Transposon%20debris%20in%20ciliate%20genomes&rft.jtitle=PLoS%20biology&rft.au=Feng,%20Yi&rft.date=2021-08-24&rft.volume=19&rft.issue=8&rft.spage=e3001354&rft.epage=e3001354&rft.pages=e3001354-e3001354&rft.issn=1545-7885&rft.eissn=1545-7885&rft_id=info:doi/10.1371/journal.pbio.3001354&rft_dat=%3Cgale_plos_%3EA674186529%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2573455172&rft_id=info:pmid/34428213&rft_galeid=A674186529&rft_doaj_id=oai_doaj_org_article_b330c4b5be3a4d43bad4a3527ce7ecc4&rfr_iscdi=true