Defective expansion and function of memory like natural killer cells in HIV+ individuals with latent tuberculosis infection

Tuberculosis (TB) is the leading cause of infectious disease related mortality, and only 10% of the infected individuals develop active disease. The likelihood of progression of latent tuberculosis infection (LTBI) to active TB disease is high in HIV infected individuals. Identification of HIV+ indi...

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Veröffentlicht in:	PloS one 2021-09, Vol.16 (9), p.e0257185-e0257185
Hauptverfasser:	Devalraju, Kamakshi Prudhula, Neela, Venkata Sanjeev Kumar, Krovvidi, Siva Sai, Vankayalapati, Ramakrishna, Valluri, Vijaya Lakshmi
Format:	Artikel
Sprache:	eng
Schlagworte:	Age groups Antigens Authorship Biology and life sciences Care and treatment CD16 antigen CD3 antigen CD56 antigen Cell activation Cytokines ESAT-6 antigen Expansion Granzyme B Health aspects Health care Health risks HIV HIV infection Human immunodeficiency virus Immune system Immunology Infections Infectious diseases Interleukin 15 Killer cells Lymphocytes Lymphocytes T Medical research Medicine and health sciences Molecular biology Monocytes Natural killer cells Pathogens Patients Public health Research and Analysis Methods Tuberculosis γ-Interferon
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