Real-life use of tocilizumab with or without corticosteroid in hospitalized patients with moderate-to-severe COVID-19 pneumonia: A retrospective cohort study

To evaluate the effectiveness of Tocilizumab (with or without corticosteroids) in a real-life context among moderate-to-severe COVID-19 patients hospitalized at the Infectious Diseases ward of two hospitals in Lazio region, Italy, during the first wave of SARS-CoV-2 pandemic. We conducted a retrospe...

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Veröffentlicht in:	PloS one 2021-09, Vol.16 (9), p.e0257376-e0257376
Hauptverfasser:	Russo, Gianluca, Solimini, Angelo, Zuccalà, Paola, Zingaropoli, Maria Antonella, Carraro, Anna, Pasculli, Patrizia, Perri, Valentina, Marocco, Raffaella, Kertusha, Blerta, Del Borgo, Cosmo, Del Giudice, Emanuela, Fondaco, Laura, Tieghi, Tiziana, D'Agostino, Claudia, Oliva, Alessandra, Vullo, Vincenzo, Ciardi, Maria Rosa, Mastroianni, Claudio Maria, Lichtner, Miriam
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis Care and treatment Clinical trials Cohort analysis Coronaviruses Corticoids Corticosteroids COVID-19 Cytokines Disease prevention Dosage and administration Evaluation Hospital patients Hospitalization Hospitals Immunomodulators Immunosuppressive agents Infectious diseases Intubation Lungs Mechanical ventilation Medicine and Health Sciences Monoclonal antibodies Multivariate analysis Observational studies Pandemics Patients Physical Sciences Pneumonia Public health Research and Analysis Methods Safety Severe acute respiratory syndrome coronavirus 2 Steroids Ventilation
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