Clinical impact of serum exosomal microRNA in liver fibrosis

Background/aim We investigated alterations in the expression of serum exosomal miRNAs with the progression of liver fibrosis and evaluated their clinical applicability as biomarkers. Methods This study prospectively enrolled 71 patients who underwent liver biopsy at an academic hospital in Korea. Ex...

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Veröffentlicht in:	PloS one 2021-09, Vol.16 (9), p.e0255672-e0255672
Hauptverfasser:	Chang, Young, Han, Jae-A, Kang, Suk Min, Jeong, Soung Won, Ryu, Tom, Park, Han Seul, Yoo, Jeong-Ju, Lee, Sae Hwan, Kim, Sang Gyune, Kim, Young Seok, Kim, Hong Soo, Jin, So Young, Ryu, Seongho, Jang, Jae Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and life sciences Biomarkers Biopsy Care and treatment Communication Diagnosis Etiology Exosomes Fibrosis Gene expression Genomes Hepatitis Internal medicine Laboratories Liver Liver diseases Medical schools Medicine Medicine and Health Sciences Methods MicroRNA MicroRNAs miRNA Next-generation sequencing Patients Polymerase chain reaction Proteins Ribonucleic acid RNA Subgroups
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