Single-cell analysis reveals the pan-cancer invasiveness-associated transition of adipose-derived stromal cells into COL11A1-expressing cancer-associated fibroblasts

During the last ten years, many research results have been referring to a particular type of cancer-associated fibroblasts associated with poor prognosis, invasiveness, metastasis and resistance to therapy in multiple cancer types, characterized by a gene expression signature with prominent presence...

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Veröffentlicht in:PLoS computational biology 2021-07, Vol.17 (7), p.e1009228-e1009228
Hauptverfasser: Zhu, Kaiyi, Cai, Lingyi, Cui, Chenqian, de los Toyos, Juan R, Anastassiou, Dimitris
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Sprache:eng
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