The 3’tsRNAs are aminoacylated: Implications for their biogenesis

Emerging evidence indicates that tRNA-derived small RNAs (tsRNAs) are involved in fine-tuning gene expression and become dysregulated in various cancers. We recently showed that the 22nt LeuCAG tsRNA from the 3' end of tRNA.sup.Leu is required for efficient translation of a ribosomal protein mR...

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Veröffentlicht in:	PLoS genetics 2021-07, Vol.17 (7), p.e1009675-e1009675
Hauptverfasser:	Liu, Ziwei, Kim, Hak Kyun, Xu, Jianpeng, Jing, Yuqing, Kay, Mark A
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biology and life sciences Biosynthesis Chemical properties E coli Exonuclease Gene expression Gene regulation Genetic aspects Genetic research Hepatocellular carcinoma Leucine-tRNA ligase Physiological aspects Post-transcription Protein synthesis Proteins Regulation Research and analysis methods Transfer RNA tRNA
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