Prevalence and risk factors for antimicrobial resistance among newborns with gram-negative sepsis

Newborn sepsis accounts for more than a third of neonatal deaths globally and one in five neonatal deaths in Ethiopia. The first-line treatment recommended by WHO is the combination of gentamicin with ampicillin or benzylpenicillin. Gram-negative bacteria (GNB) are increasingly resistant to previous...

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Veröffentlicht in:	PloS one 2021-08, Vol.16 (8), p.e0255410
Hauptverfasser:	Solomon, Semaria, Akeju, Oluwasefunmi, Odumade, Oludare A, Ambachew, Rozina, Gebreyohannes, Zenebe, Van Wickle, Kimi, Abayneh, Mahlet, Metaferia, Gesit, Carvalho, Maria J, Thomson, Kathryn, Sands, Kirsty, Walsh, Timothy R, Milton, Rebecca, Goddard, Frederick G B, Bekele, Delayehu, Chan, Grace J
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Amikacin Ampicillin Ampicillin - pharmacology Anti-Bacterial Agents - pharmacology Antibiotic resistance Antibiotics Antimicrobial agents Antimicrobial resistance Bacteremia Bacteria Benzylpenicillin Biology and Life Sciences Birth weight Cefotaxime Cephalosporins Cephalosporins - pharmacology Decision making Diseases Drug resistance Drug resistance in microorganisms Drug Resistance, Multiple, Bacterial Drug therapy E coli Environmental factors Ethiopia - epidemiology Fatalities Female Gentamicin Gentamicins - pharmacology Gram-negative bacteria Gram-Negative Bacteria - drug effects Gram-Negative Bacteria - growth & development Gram-negative bacterial infections Gram-Negative Bacterial Infections - epidemiology Gram-Negative Bacterial Infections - microbiology Gram-positive bacteria Health risks Humans Imipenem Infant mortality Infant, Newborn Infants (Newborn) Infections Klebsiella Laboratories Male Medical schools Medicine and Health Sciences Microbial Viability - drug effects Multidrug resistance Neonatal Sepsis - epidemiology Neonatal Sepsis - microbiology Neonates Newborn babies Pediatric research Penicillin G - pharmacology Piperacillin Piperacillin-tazobactam Pregnancy Prevalence Public health Resistance factors Risk analysis Risk factors Sepsis Statistics Tazobactam Tertiary Care Centers Zoology
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