A tightly clustered hepatitis E virus genotype 1a is associated with endemic and outbreak infections in Bangladesh

Hepatitis E virus (HEV) infection is endemic in Bangladesh and there are occasional outbreaks. The molecular characteristics and pathogenesis of endemic and outbreak HEV strains are poorly understood. We compared the genetic relatedness and virulence associated mutations of endemic HEV strains with...

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Veröffentlicht in:	PloS one 2021-07, Vol.16 (7), p.e0255054-e0255054
Hauptverfasser:	Hoa, Trang Nguyen, Munshi, Saif Ullah, Ngoc, Khanh Nguyen, Ngoc, Chau Le, Thanh, Thanh Tran Thi, Akther, Tahmina, Tabassum, Shahina, Parvin, Nilufa, Baker, Stephen, Rahman, Motiur
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antibodies Antigenicity Biology and life sciences Cell recognition Clusters Computer and Information Sciences Disease Epidemics Epitopes Food contamination & poisoning Gene sequencing Genetic aspects Genomes Genotype & phenotype Genotypes Hepatitis Hepatitis E virus Hospitals Immunoglobulin M Infections Lymphocytes Lymphocytes T Medicine and health sciences Mutation Neutralization Nucleotide sequence Open reading frames Outbreaks Pathogenesis Patients People and Places Phylogenetics Phylogeny Proteins Research and analysis methods Ribavirin Ribonucleic acid RNA Strains (organisms) Tropical diseases Virulence Virulence (Microbiology) Viruses Whole genome sequencing
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