Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial

To determine if men who have sex with men (MSM) with cocaine use disorder (CUD) and actively-using cocaine could be enrolled and retained in a pharmacologic intervention trial of lorcaserin-a novel 5-HT2cR agonist-and determine the degree to which participants would adhere to study procedures. This...

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Veröffentlicht in:	PloS one 2021-07, Vol.16 (7), p.e0254724
Hauptverfasser:	Santos, Glenn-Milo, Ikeda, Janet, Coffin, Phillip, Walker, John E, Matheson, Tim, McLaughlin, Matthew, Jain, Jennifer, Vittinghoff, Eric, Batki, Steven L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agonists Behavior Behavioral sciences Benzazepines - administration & dosage Benzazepines - adverse effects Benzazepines - therapeutic use Biology and Life Sciences Cancer Cardiovascular disease Care and treatment Clinical trials Cocaine Cocaine-Related Disorders - drug therapy Complications and side effects COVID-19 Delayed-Action Preparations Dopamine Double-Blind Method Double-blind studies Drug use Evaluation FDA approval Gays & lesbians Health aspects Health risks HIV Homosexuality, Male Human immunodeficiency virus Humans Impulsivity Lorcaserin Male Medicine and Health Sciences Mens health Microelectromechanical systems Middle Aged MSM (Men who have sex with men) Overweight Patient outcomes People and Places Pharmacology Physical Sciences Pilot Projects Placebos Public health Risk assessment Risk taking Serotonin S2 receptors Substance abuse Substance use Urine Young Adult
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