DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial

Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study was to identify methylation loci associated with the time to recurrent cerebro-...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2021-07, Vol.16 (7), p.e0254562-e0254562
Hauptverfasser:	Davis Armstrong, Nicole M., Chen, Wei-Min, Hsu, Fang-Chi, Brewer, Michael S., Cullell, Natalia, Fernández-Cadenas, Israel, Williams, Stephen R., Sale, Michèle M., Worrall, Bradford B., Keene, Keith L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antithrombin Biological markers Biology and life sciences Biomarkers Cardiovascular disease Cardiovascular diseases CpG islands Deoxyribonucleic acid DNA DNA methylation DNA microarrays Epigenetics Genetic aspects Heart attacks Loci Medicine and Health Sciences Methylation Minority & ethnic groups Network analysis Physical Sciences Prevention Prothrombin Regression analysis Regression models Research and Analysis Methods Secondary analysis Stroke Stroke (Disease) t-Plasminogen activator Thrombin Triglycerides
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!