Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae
Ayapana triplinervis is a plant species used in traditional medicine and in mystical-religious rituals by traditional communities in the Amazon. The aim of this study are to develop a nano-emulsion containing essential oil from A. triplinervis morphotypes, to evaluate larvicidal activity against Aed...
Gespeichert in:
| Veröffentlicht in: | PloS one 2021-07, Vol.16 (7), p.e0254225 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 7 |
| container_start_page | e0254225 |
| container_title | PloS one |
| container_volume | 16 |
| creator | Lobato Rodrigues, Alex Bruno Martins, Rosany Lopes Rabelo, Érica de Menezes Tomazi, Rosana Santos, Lizandra Lima Brandão, Lethícia Barreto Faustino, Cleidjane Gomes Ferreira Farias, Ana Luzia Dos Santos, Cleydson Breno Rodrigues de Castro Cantuária, Patrick Galardo, Allan Kardec Ribeiro de Almeida, Sheylla Susan Moreira da Silva |
| description | Ayapana triplinervis is a plant species used in traditional medicine and in mystical-religious rituals by traditional communities in the Amazon. The aim of this study are to develop a nano-emulsion containing essential oil from A. triplinervis morphotypes, to evaluate larvicidal activity against Aedes aegypti and acute oral toxicity in Swiss albino mice (Mus musculus). The essential oils were extracted by steam dragging, identified by gas chromatography coupled to mass spectrometry, and nano-emulsions were prepared using the low energy method. Phytochemical analyses indicated the major compounds, expressed as area percentage, β-Caryophyllene (45.93%) and Thymohydroquinone Dimethyl Ether (32.93%) in morphotype A; and Thymohydroquinone Dimethyl Ether (84.53%) was found in morphotype B. Morphotype A essential oil nano-emulsion showed a particle size of 101.400 ± 0.971 nm (polydispersity index = 0.124 ± 0.009 and zeta potential = -19.300 ± 0.787 mV). Morphotype B essential oil nano-emulsion had a particle size of 104.567 ± 0.416 nm (polydispersity index = 0.168 ± 0.016 and zeta potential = -27.700 ± 1.307 mV). Histomorphological analyses showed the presence of inflammatory cells in the liver of animals treated with morphotype A essential oil nano-emulsion (MAEON) and morphotype B essential oil nano-emulsion (MBEON). Congestion and the presence of transudate with leukocyte infiltration in the lung of animals treated with MAEON were observed. The nano-emulsions containing essential oils of A. triplinervis morphotypes showed an effective nanobiotechnological product in the chemical control of A. aegypti larvae with minimal toxicological action for non-target mammals. |
| doi_str_mv | 10.1371/journal.pone.0254225 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2549937064</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A667980242</galeid><doaj_id>oai_doaj_org_article_081064004d474a5cbe08abb1e2c1c1dc</doaj_id><sourcerecordid>A667980242</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-6035160aea01c411b6c5165827e16b88c01e3f2b36843b9b71a0a3f66897cbe63</originalsourceid><addsrcrecordid>eNqNk02L2zAQhk1p6W7T_oPSCgqlPSSVLFu2Lwth-xVYWOjXVYzlcaJFkbySHZp_X7nxLknZQ_HBlvy872hmNEnyktEF4wX7cOMGb8EsOmdxQdM8S9P8UXLOKp7ORUr546Pvs-RZCDeU5rwU4mlyxrM0S3lanie3H3GHxnVbtD1xLbFg3Ry3gwna2UBqCNgQZ8lyDx1YIL3XndEW_U4HgiFEmQZDnDakdZ70GyTK2d47M7otscFAANf7rtfEgN8BPk-etGACvpjes-Tn508_Lr_Or66_rC6XV3MlqrSfC8pzJiggUKYyxmqh4jov0wKZqMtSUYa8TWsuyozXVV0woMBbIcqqUDUKPkteH3w744KcqhVkLFRV8YKKLBKrA9E4uJGd11vwe-lAy78bzq8l-F4rg5KWLCoozZqsyCCPAWgJdc0wVUyxRkWviynaUG-xUbEuHsyJ6ekfqzdy7XYyJkQZH4_7bjLw7nbA0MutDgqNAYtuGM-dxyZXIssj-uYf9OHsJmoNMQFtWxfjqtFULoUoqpKOd2CWLB6g4tPgVsdOYqvj_ong_Ylg7Db-7tcwhCBX37_9P3v965R9e8RuEEy_Cc4M_XgPT8HsACrvQvDY3heZUTlOxl015DgZcpqMKHt13KB70d0o8D8C8wjV</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2549937064</pqid></control><display><type>article</type><title>Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae</title><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS) Journals Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Lobato Rodrigues, Alex Bruno ; Martins, Rosany Lopes ; Rabelo, Érica de Menezes ; Tomazi, Rosana ; Santos, Lizandra Lima ; Brandão, Lethícia Barreto ; Faustino, Cleidjane Gomes ; Ferreira Farias, Ana Luzia ; Dos Santos, Cleydson Breno Rodrigues ; de Castro Cantuária, Patrick ; Galardo, Allan Kardec Ribeiro ; de Almeida, Sheylla Susan Moreira da Silva</creator><contributor>Hasaballah, Ahmed Ibrahim</contributor><creatorcontrib>Lobato Rodrigues, Alex Bruno ; Martins, Rosany Lopes ; Rabelo, Érica de Menezes ; Tomazi, Rosana ; Santos, Lizandra Lima ; Brandão, Lethícia Barreto ; Faustino, Cleidjane Gomes ; Ferreira Farias, Ana Luzia ; Dos Santos, Cleydson Breno Rodrigues ; de Castro Cantuária, Patrick ; Galardo, Allan Kardec Ribeiro ; de Almeida, Sheylla Susan Moreira da Silva ; Hasaballah, Ahmed Ibrahim</creatorcontrib><description>Ayapana triplinervis is a plant species used in traditional medicine and in mystical-religious rituals by traditional communities in the Amazon. The aim of this study are to develop a nano-emulsion containing essential oil from A. triplinervis morphotypes, to evaluate larvicidal activity against Aedes aegypti and acute oral toxicity in Swiss albino mice (Mus musculus). The essential oils were extracted by steam dragging, identified by gas chromatography coupled to mass spectrometry, and nano-emulsions were prepared using the low energy method. Phytochemical analyses indicated the major compounds, expressed as area percentage, β-Caryophyllene (45.93%) and Thymohydroquinone Dimethyl Ether (32.93%) in morphotype A; and Thymohydroquinone Dimethyl Ether (84.53%) was found in morphotype B. Morphotype A essential oil nano-emulsion showed a particle size of 101.400 ± 0.971 nm (polydispersity index = 0.124 ± 0.009 and zeta potential = -19.300 ± 0.787 mV). Morphotype B essential oil nano-emulsion had a particle size of 104.567 ± 0.416 nm (polydispersity index = 0.168 ± 0.016 and zeta potential = -27.700 ± 1.307 mV). Histomorphological analyses showed the presence of inflammatory cells in the liver of animals treated with morphotype A essential oil nano-emulsion (MAEON) and morphotype B essential oil nano-emulsion (MBEON). Congestion and the presence of transudate with leukocyte infiltration in the lung of animals treated with MAEON were observed. The nano-emulsions containing essential oils of A. triplinervis morphotypes showed an effective nanobiotechnological product in the chemical control of A. aegypti larvae with minimal toxicological action for non-target mammals.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0254225</identifier><identifier>PMID: 34242328</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Aedes - drug effects ; Aedes aegypti ; Animals ; Ayapana ; Biology and Life Sciences ; Caryophyllene ; Chemical control ; Compositae ; Composition ; Dimethyl ether ; Emulsions ; Energy methods ; Engineering and Technology ; Essences and essential oils ; Essential oils ; Evaluation ; Gas chromatography ; Health sciences ; Hepatocytes ; Infections ; Inflammation ; Insecticides ; Insecticides - chemistry ; Insecticides - pharmacology ; Larva - drug effects ; Larvae ; Leukocytes ; Mass spectrometry ; Mass spectroscopy ; Medicinal plants ; Medicine and Health Sciences ; Metabolites ; Mice ; Mosquito Control - methods ; Mosquitoes ; Nanoemulsions ; Nanoparticles - chemistry ; Oils & fats ; Oils, Volatile - administration & dosage ; Oils, Volatile - chemistry ; Oils, Volatile - pharmacology ; Particle Size ; Pharmaceutical industry ; Physical Sciences ; Plant species ; Polydispersity ; Properties ; Public health ; Steam ; Toxicity ; Zeta potential</subject><ispartof>PloS one, 2021-07, Vol.16 (7), p.e0254225</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 Lobato Rodrigues et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 Lobato Rodrigues et al 2021 Lobato Rodrigues et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-6035160aea01c411b6c5165827e16b88c01e3f2b36843b9b71a0a3f66897cbe63</citedby><cites>FETCH-LOGICAL-c692t-6035160aea01c411b6c5165827e16b88c01e3f2b36843b9b71a0a3f66897cbe63</cites><orcidid>0000-0003-2170-1773 ; 0000-0001-7708-6576 ; 0000-0002-7687-8288</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270136/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270136/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2102,2928,23866,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34242328$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Hasaballah, Ahmed Ibrahim</contributor><creatorcontrib>Lobato Rodrigues, Alex Bruno</creatorcontrib><creatorcontrib>Martins, Rosany Lopes</creatorcontrib><creatorcontrib>Rabelo, Érica de Menezes</creatorcontrib><creatorcontrib>Tomazi, Rosana</creatorcontrib><creatorcontrib>Santos, Lizandra Lima</creatorcontrib><creatorcontrib>Brandão, Lethícia Barreto</creatorcontrib><creatorcontrib>Faustino, Cleidjane Gomes</creatorcontrib><creatorcontrib>Ferreira Farias, Ana Luzia</creatorcontrib><creatorcontrib>Dos Santos, Cleydson Breno Rodrigues</creatorcontrib><creatorcontrib>de Castro Cantuária, Patrick</creatorcontrib><creatorcontrib>Galardo, Allan Kardec Ribeiro</creatorcontrib><creatorcontrib>de Almeida, Sheylla Susan Moreira da Silva</creatorcontrib><title>Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Ayapana triplinervis is a plant species used in traditional medicine and in mystical-religious rituals by traditional communities in the Amazon. The aim of this study are to develop a nano-emulsion containing essential oil from A. triplinervis morphotypes, to evaluate larvicidal activity against Aedes aegypti and acute oral toxicity in Swiss albino mice (Mus musculus). The essential oils were extracted by steam dragging, identified by gas chromatography coupled to mass spectrometry, and nano-emulsions were prepared using the low energy method. Phytochemical analyses indicated the major compounds, expressed as area percentage, β-Caryophyllene (45.93%) and Thymohydroquinone Dimethyl Ether (32.93%) in morphotype A; and Thymohydroquinone Dimethyl Ether (84.53%) was found in morphotype B. Morphotype A essential oil nano-emulsion showed a particle size of 101.400 ± 0.971 nm (polydispersity index = 0.124 ± 0.009 and zeta potential = -19.300 ± 0.787 mV). Morphotype B essential oil nano-emulsion had a particle size of 104.567 ± 0.416 nm (polydispersity index = 0.168 ± 0.016 and zeta potential = -27.700 ± 1.307 mV). Histomorphological analyses showed the presence of inflammatory cells in the liver of animals treated with morphotype A essential oil nano-emulsion (MAEON) and morphotype B essential oil nano-emulsion (MBEON). Congestion and the presence of transudate with leukocyte infiltration in the lung of animals treated with MAEON were observed. The nano-emulsions containing essential oils of A. triplinervis morphotypes showed an effective nanobiotechnological product in the chemical control of A. aegypti larvae with minimal toxicological action for non-target mammals.</description><subject>Aedes - drug effects</subject><subject>Aedes aegypti</subject><subject>Animals</subject><subject>Ayapana</subject><subject>Biology and Life Sciences</subject><subject>Caryophyllene</subject><subject>Chemical control</subject><subject>Compositae</subject><subject>Composition</subject><subject>Dimethyl ether</subject><subject>Emulsions</subject><subject>Energy methods</subject><subject>Engineering and Technology</subject><subject>Essences and essential oils</subject><subject>Essential oils</subject><subject>Evaluation</subject><subject>Gas chromatography</subject><subject>Health sciences</subject><subject>Hepatocytes</subject><subject>Infections</subject><subject>Inflammation</subject><subject>Insecticides</subject><subject>Insecticides - chemistry</subject><subject>Insecticides - pharmacology</subject><subject>Larva - drug effects</subject><subject>Larvae</subject><subject>Leukocytes</subject><subject>Mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Medicinal plants</subject><subject>Medicine and Health Sciences</subject><subject>Metabolites</subject><subject>Mice</subject><subject>Mosquito Control - methods</subject><subject>Mosquitoes</subject><subject>Nanoemulsions</subject><subject>Nanoparticles - chemistry</subject><subject>Oils & fats</subject><subject>Oils, Volatile - administration & dosage</subject><subject>Oils, Volatile - chemistry</subject><subject>Oils, Volatile - pharmacology</subject><subject>Particle Size</subject><subject>Pharmaceutical industry</subject><subject>Physical Sciences</subject><subject>Plant species</subject><subject>Polydispersity</subject><subject>Properties</subject><subject>Public health</subject><subject>Steam</subject><subject>Toxicity</subject><subject>Zeta potential</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk02L2zAQhk1p6W7T_oPSCgqlPSSVLFu2Lwth-xVYWOjXVYzlcaJFkbySHZp_X7nxLknZQ_HBlvy872hmNEnyktEF4wX7cOMGb8EsOmdxQdM8S9P8UXLOKp7ORUr546Pvs-RZCDeU5rwU4mlyxrM0S3lanie3H3GHxnVbtD1xLbFg3Ry3gwna2UBqCNgQZ8lyDx1YIL3XndEW_U4HgiFEmQZDnDakdZ70GyTK2d47M7otscFAANf7rtfEgN8BPk-etGACvpjes-Tn508_Lr_Or66_rC6XV3MlqrSfC8pzJiggUKYyxmqh4jov0wKZqMtSUYa8TWsuyozXVV0woMBbIcqqUDUKPkteH3w744KcqhVkLFRV8YKKLBKrA9E4uJGd11vwe-lAy78bzq8l-F4rg5KWLCoozZqsyCCPAWgJdc0wVUyxRkWviynaUG-xUbEuHsyJ6ekfqzdy7XYyJkQZH4_7bjLw7nbA0MutDgqNAYtuGM-dxyZXIssj-uYf9OHsJmoNMQFtWxfjqtFULoUoqpKOd2CWLB6g4tPgVsdOYqvj_ong_Ylg7Db-7tcwhCBX37_9P3v965R9e8RuEEy_Cc4M_XgPT8HsACrvQvDY3heZUTlOxl015DgZcpqMKHt13KB70d0o8D8C8wjV</recordid><startdate>20210709</startdate><enddate>20210709</enddate><creator>Lobato Rodrigues, Alex Bruno</creator><creator>Martins, Rosany Lopes</creator><creator>Rabelo, Érica de Menezes</creator><creator>Tomazi, Rosana</creator><creator>Santos, Lizandra Lima</creator><creator>Brandão, Lethícia Barreto</creator><creator>Faustino, Cleidjane Gomes</creator><creator>Ferreira Farias, Ana Luzia</creator><creator>Dos Santos, Cleydson Breno Rodrigues</creator><creator>de Castro Cantuária, Patrick</creator><creator>Galardo, Allan Kardec Ribeiro</creator><creator>de Almeida, Sheylla Susan Moreira da Silva</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0003-2170-1773</orcidid><orcidid>https://orcid.org/0000-0001-7708-6576</orcidid><orcidid>https://orcid.org/0000-0002-7687-8288</orcidid></search><sort><creationdate>20210709</creationdate><title>Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae</title><author>Lobato Rodrigues, Alex Bruno ; Martins, Rosany Lopes ; Rabelo, Érica de Menezes ; Tomazi, Rosana ; Santos, Lizandra Lima ; Brandão, Lethícia Barreto ; Faustino, Cleidjane Gomes ; Ferreira Farias, Ana Luzia ; Dos Santos, Cleydson Breno Rodrigues ; de Castro Cantuária, Patrick ; Galardo, Allan Kardec Ribeiro ; de Almeida, Sheylla Susan Moreira da Silva</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-6035160aea01c411b6c5165827e16b88c01e3f2b36843b9b71a0a3f66897cbe63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Aedes - drug effects</topic><topic>Aedes aegypti</topic><topic>Animals</topic><topic>Ayapana</topic><topic>Biology and Life Sciences</topic><topic>Caryophyllene</topic><topic>Chemical control</topic><topic>Compositae</topic><topic>Composition</topic><topic>Dimethyl ether</topic><topic>Emulsions</topic><topic>Energy methods</topic><topic>Engineering and Technology</topic><topic>Essences and essential oils</topic><topic>Essential oils</topic><topic>Evaluation</topic><topic>Gas chromatography</topic><topic>Health sciences</topic><topic>Hepatocytes</topic><topic>Infections</topic><topic>Inflammation</topic><topic>Insecticides</topic><topic>Insecticides - chemistry</topic><topic>Insecticides - pharmacology</topic><topic>Larva - drug effects</topic><topic>Larvae</topic><topic>Leukocytes</topic><topic>Mass spectrometry</topic><topic>Mass spectroscopy</topic><topic>Medicinal plants</topic><topic>Medicine and Health Sciences</topic><topic>Metabolites</topic><topic>Mice</topic><topic>Mosquito Control - methods</topic><topic>Mosquitoes</topic><topic>Nanoemulsions</topic><topic>Nanoparticles - chemistry</topic><topic>Oils & fats</topic><topic>Oils, Volatile - administration & dosage</topic><topic>Oils, Volatile - chemistry</topic><topic>Oils, Volatile - pharmacology</topic><topic>Particle Size</topic><topic>Pharmaceutical industry</topic><topic>Physical Sciences</topic><topic>Plant species</topic><topic>Polydispersity</topic><topic>Properties</topic><topic>Public health</topic><topic>Steam</topic><topic>Toxicity</topic><topic>Zeta potential</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lobato Rodrigues, Alex Bruno</creatorcontrib><creatorcontrib>Martins, Rosany Lopes</creatorcontrib><creatorcontrib>Rabelo, Érica de Menezes</creatorcontrib><creatorcontrib>Tomazi, Rosana</creatorcontrib><creatorcontrib>Santos, Lizandra Lima</creatorcontrib><creatorcontrib>Brandão, Lethícia Barreto</creatorcontrib><creatorcontrib>Faustino, Cleidjane Gomes</creatorcontrib><creatorcontrib>Ferreira Farias, Ana Luzia</creatorcontrib><creatorcontrib>Dos Santos, Cleydson Breno Rodrigues</creatorcontrib><creatorcontrib>de Castro Cantuária, Patrick</creatorcontrib><creatorcontrib>Galardo, Allan Kardec Ribeiro</creatorcontrib><creatorcontrib>de Almeida, Sheylla Susan Moreira da Silva</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lobato Rodrigues, Alex Bruno</au><au>Martins, Rosany Lopes</au><au>Rabelo, Érica de Menezes</au><au>Tomazi, Rosana</au><au>Santos, Lizandra Lima</au><au>Brandão, Lethícia Barreto</au><au>Faustino, Cleidjane Gomes</au><au>Ferreira Farias, Ana Luzia</au><au>Dos Santos, Cleydson Breno Rodrigues</au><au>de Castro Cantuária, Patrick</au><au>Galardo, Allan Kardec Ribeiro</au><au>de Almeida, Sheylla Susan Moreira da Silva</au><au>Hasaballah, Ahmed Ibrahim</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2021-07-09</date><risdate>2021</risdate><volume>16</volume><issue>7</issue><spage>e0254225</spage><pages>e0254225-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Ayapana triplinervis is a plant species used in traditional medicine and in mystical-religious rituals by traditional communities in the Amazon. The aim of this study are to develop a nano-emulsion containing essential oil from A. triplinervis morphotypes, to evaluate larvicidal activity against Aedes aegypti and acute oral toxicity in Swiss albino mice (Mus musculus). The essential oils were extracted by steam dragging, identified by gas chromatography coupled to mass spectrometry, and nano-emulsions were prepared using the low energy method. Phytochemical analyses indicated the major compounds, expressed as area percentage, β-Caryophyllene (45.93%) and Thymohydroquinone Dimethyl Ether (32.93%) in morphotype A; and Thymohydroquinone Dimethyl Ether (84.53%) was found in morphotype B. Morphotype A essential oil nano-emulsion showed a particle size of 101.400 ± 0.971 nm (polydispersity index = 0.124 ± 0.009 and zeta potential = -19.300 ± 0.787 mV). Morphotype B essential oil nano-emulsion had a particle size of 104.567 ± 0.416 nm (polydispersity index = 0.168 ± 0.016 and zeta potential = -27.700 ± 1.307 mV). Histomorphological analyses showed the presence of inflammatory cells in the liver of animals treated with morphotype A essential oil nano-emulsion (MAEON) and morphotype B essential oil nano-emulsion (MBEON). Congestion and the presence of transudate with leukocyte infiltration in the lung of animals treated with MAEON were observed. The nano-emulsions containing essential oils of A. triplinervis morphotypes showed an effective nanobiotechnological product in the chemical control of A. aegypti larvae with minimal toxicological action for non-target mammals.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>34242328</pmid><doi>10.1371/journal.pone.0254225</doi><tpages>e0254225</tpages><orcidid>https://orcid.org/0000-0003-2170-1773</orcidid><orcidid>https://orcid.org/0000-0001-7708-6576</orcidid><orcidid>https://orcid.org/0000-0002-7687-8288</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2021-07, Vol.16 (7), p.e0254225 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2549937064 |
| source | MEDLINE; DOAJ Directory of Open Access Journals; Public Library of Science (PLoS) Journals Open Access; EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Aedes - drug effects Aedes aegypti Animals Ayapana Biology and Life Sciences Caryophyllene Chemical control Compositae Composition Dimethyl ether Emulsions Energy methods Engineering and Technology Essences and essential oils Essential oils Evaluation Gas chromatography Health sciences Hepatocytes Infections Inflammation Insecticides Insecticides - chemistry Insecticides - pharmacology Larva - drug effects Larvae Leukocytes Mass spectrometry Mass spectroscopy Medicinal plants Medicine and Health Sciences Metabolites Mice Mosquito Control - methods Mosquitoes Nanoemulsions Nanoparticles - chemistry Oils & fats Oils, Volatile - administration & dosage Oils, Volatile - chemistry Oils, Volatile - pharmacology Particle Size Pharmaceutical industry Physical Sciences Plant species Polydispersity Properties Public health Steam Toxicity Zeta potential |
| title | Development of nano-emulsions based on Ayapana triplinervis essential oil for the control of Aedes aegypti larvae |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T14%3A37%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20nano-emulsions%20based%20on%20Ayapana%20triplinervis%20essential%20oil%20for%20the%20control%20of%20Aedes%20aegypti%20larvae&rft.jtitle=PloS%20one&rft.au=Lobato%20Rodrigues,%20Alex%20Bruno&rft.date=2021-07-09&rft.volume=16&rft.issue=7&rft.spage=e0254225&rft.pages=e0254225-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0254225&rft_dat=%3Cgale_plos_%3EA667980242%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2549937064&rft_id=info:pmid/34242328&rft_galeid=A667980242&rft_doaj_id=oai_doaj_org_article_081064004d474a5cbe08abb1e2c1c1dc&rfr_iscdi=true |