Formulation of tunable size PLGA-PEG nanoparticles for drug delivery using microfluidic technology

Amphiphilic block co-polymer nanoparticles are interesting candidates for drug delivery as a result of their unique properties such as the size, modularity, biocompatibility and drug loading capacity. They can be rapidly formulated in a nanoprecipitation process based on self-assembly, resulting in...

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Veröffentlicht in:	PloS one 2021-06, Vol.16 (6), p.e0251821
Hauptverfasser:	Mares, Adrianna Glinkowska, Pacassoni, Gaia, Marti, Josep Samitier, Pujals, Silvia, Albertazzi, Lorenzo
Format:	Artikel
Sprache:	eng
Schlagworte:	Aerodynamics Aerospace engineering Analysis Biocompatibility Bioengineering Biomaterials Biomedical engineering Biomedical materials Breast Neoplasms - drug therapy Breast Neoplasms - pathology Computational fluid dynamics Design modifications Drug Carriers - chemistry Drug delivery Drug Delivery Systems Drugs Editing Engineering Engineering and Technology Evaluation Female Flow velocity Fluid dynamics Fluid flow Humans Hydrodynamics Ligands Liquids MCF-7 Cells Medical research Medical treatment Medicine and Health Sciences Microfluidics Microfluidics - methods Nanoparticles Nanoparticles - administration & dosage Nanoparticles - chemistry Nanotechnology Particle formation Physical Sciences Physics Polyesters - chemistry Polyethylene glycol Polyethylene Glycols - chemistry Polylactide-co-glycolide Polymers Polymers - chemistry Research and Analysis Methods Research facilities Reviews Science and technology Solubility Solvents Stream discharge Stream flow Technology Vehicles Water runoff
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