Evaluation of polygenic prediction methodology within a reference-standardized framework

The predictive utility of polygenic scores is increasing, and many polygenic scoring methods are available, but it is unclear which method performs best. This study evaluates the predictive utility of polygenic scoring methods within a reference-standardized framework, which uses a common set of var...

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Veröffentlicht in:PLoS genetics 2021-05, Vol.17 (5), p.e1009021
Hauptverfasser: Pain, Oliver, Glanville, Kylie P, Hagenaars, Saskia P, Selzam, Saskia, Fürtjes, Anna E, Gaspar, Héléna A, Coleman, Jonathan R I, Rimfeld, Kaili, Breen, Gerome, Plomin, Robert, Folkersen, Lasse, Lewis, Cathryn M
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Sprache:eng
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