Assessment of the causal relevance of ECG parameters for risk of atrial fibrillation: A mendelian randomisation study

Atrial electrical and structural remodelling in older individuals with cardiovascular risk factors has been associated with changes in surface electrocardiographic (ECG) parameters (e.g., prolongation of the PR interval) and higher risks of atrial fibrillation (AF). However, it has been difficult to...

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Veröffentlicht in:	PLoS medicine 2021-05, Vol.18 (5), p.e1003572-e1003572
Hauptverfasser:	Gajendragadkar, Parag Ravindra, Von Ende, Adam, Ibrahim, Maysson, Valdes-Marquez, Elsa, Camm, Christian Fielder, Murgia, Federico, Stiby, Alexander, Casadei, Barbara, Hopewell, Jemma C
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alleles Atrial fibrillation Atrial Fibrillation - epidemiology Atrial Fibrillation - genetics Biobanks Biology and Life Sciences Cardiac arrhythmia Cardiovascular disease Catheters Codes Congestive heart failure Coronary artery disease Diabetes mellitus Diagnosis Drug therapy EKG Electrocardiogram Electrocardiography Electrocardiography - statistics & numerical data Female Fibrillation Genomes Heart failure Humans Hypertension Magnetic resonance imaging Male Medicine and Health Sciences Mendelian Randomization Analysis Methods Middle Aged Observational studies Physical Sciences Prevalence Research and Analysis Methods Risk Assessment - methods Risk factors Statistics United Kingdom - epidemiology
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