Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study
We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwe...
Gespeichert in:
| Veröffentlicht in: | PloS one 2021-06, Vol.16 (6), p.e0253165-e0253165 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0253165 |
|---|---|
| container_issue | 6 |
| container_start_page | e0253165 |
| container_title | PloS one |
| container_volume | 16 |
| creator | Jo, Hyun Ho Min, Changwook Kyoung, Dae-Sung Park, Min-Ae Kim, Sang Gyune Kim, Young Seok Chang, Young Jeong, Soung Won Jang, Jae Young Lee, Sae Hwan Kim, Hong Soo Jun, Baek Gyu Kim, Young Don Cheon, Gab Jin Yoo, Jeong-Ju |
| description | We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56-1.79, P |
| doi_str_mv | 10.1371/journal.pone.0253165 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2540711648</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A665196234</galeid><doaj_id>oai_doaj_org_article_8dbc34b708564df68eba844103d82d40</doaj_id><sourcerecordid>A665196234</sourcerecordid><originalsourceid>FETCH-LOGICAL-c669t-13684b7ee0b29c81824ecac0a5045230b9554ca331b93515d3d0fa8ef43129af3</originalsourceid><addsrcrecordid>eNqNk12L1DAUhoso7rr6DwQLgujFjPne1AthWPwYXFjw6zakyWknQ9uMSbq6_97MTpWp7IXkIjnJ874nOeQUxVOMlpie49dbP4ZBd8udH2CJCKdY8HvFKa4oWQiC6P2j9UnxKMYtQpxKIR4WJ5RhwqVAp0Vc2WsIEUo_JuN7iKVuEoQyjqGF4HLshnKnk4MhxfKnS5uyc1lRGhfCxkeXBb0f2vKTD6Az6ndjl3E_vClXR9Gi1hFsGdNobx4XDxrdRXgyzWfFt_fvvl58XFxefVhfrC4XRogqLTAVktXnAKgmlZFYEgZGG6Q5YpxQVFecM6MpxXVFOeaWWtRoCQ2jmFS6oWfFs4PvrvNRTfWKinCGzjEWTGZifSCs11u1C67X4UZ57dTthg-t0iE504GStjY0XwdJLphthIRaS8YwolYSy1D2ejtlG-serMkFC7qbmc5PBrdRrb9WkiBS8b3By8kg-B8jxKR6Fw10nR7Aj7f3xpRgzERGn_-D3v26iWp1foAbGp_zmr2pWgnBcSUIZZla3kHlYaF3Jn-uxuX9meDVTJCZBL9Sq8cY1frL5_9nr77P2RdH7AZ0lzbRd-P--8Q5yA6gCT7GAM3fImOk9r3xpxpq3xtq6g36G6iaAFM</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2540711648</pqid></control><display><type>article</type><title>Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study</title><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Public Library of Science (PLoS)</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Jo, Hyun Ho ; Min, Changwook ; Kyoung, Dae-Sung ; Park, Min-Ae ; Kim, Sang Gyune ; Kim, Young Seok ; Chang, Young ; Jeong, Soung Won ; Jang, Jae Young ; Lee, Sae Hwan ; Kim, Hong Soo ; Jun, Baek Gyu ; Kim, Young Don ; Cheon, Gab Jin ; Yoo, Jeong-Ju</creator><contributor>Yeh, Chun Chieh</contributor><creatorcontrib>Jo, Hyun Ho ; Min, Changwook ; Kyoung, Dae-Sung ; Park, Min-Ae ; Kim, Sang Gyune ; Kim, Young Seok ; Chang, Young ; Jeong, Soung Won ; Jang, Jae Young ; Lee, Sae Hwan ; Kim, Hong Soo ; Jun, Baek Gyu ; Kim, Young Don ; Cheon, Gab Jin ; Yoo, Jeong-Ju ; Yeh, Chun Chieh</creatorcontrib><description>We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56-1.79, P<0.001], especially in-hospital mortality. In liver cirrhosis group, presence of decompensation or varices showed significantly increased postoperative complication or mortality. Adverse outcomes in patients with cirrhosis was the highest in patients who underwent otorhinolaryngology surgery (aOR 1.86), followed by neurosurgery (aOR 1.72), thoracic and cardiovascular surgery (aOR 1.56), and plastic surgery (aOR 1.36). The adverse outcomes of patients with cirrhosis is significantly high after surgery, despite advances in cirrhosis treatment.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0253165</identifier><identifier>PMID: 34125860</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Adverse events ; Antiviral agents ; Biology and Life Sciences ; Chronic obstructive pulmonary disease ; Cirrhosis ; Codes ; Complications and side effects ; Disease ; Fatty liver ; Gastroenterology ; Health insurance ; Health risks ; Hepatology ; Hospitals ; Internal medicine ; Life expectancy ; Life span ; Liver ; Liver cirrhosis ; Liver diseases ; Medicine ; Medicine and Health Sciences ; Mortality ; Patient outcomes ; Patients ; Population ; Population studies ; Population-based studies ; Prognosis ; Regression analysis ; Risk analysis ; Risk factors ; Surgery ; Variables</subject><ispartof>PloS one, 2021-06, Vol.16 (6), p.e0253165-e0253165</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 Jo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 Jo et al 2021 Jo et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c669t-13684b7ee0b29c81824ecac0a5045230b9554ca331b93515d3d0fa8ef43129af3</citedby><cites>FETCH-LOGICAL-c669t-13684b7ee0b29c81824ecac0a5045230b9554ca331b93515d3d0fa8ef43129af3</cites><orcidid>0000-0002-7113-3623 ; 0000-0002-7802-0381 ; 0000-0003-3993-716X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202950/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8202950/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,725,778,782,862,883,2098,2917,23849,27907,27908,53774,53776,79351,79352</link.rule.ids></links><search><contributor>Yeh, Chun Chieh</contributor><creatorcontrib>Jo, Hyun Ho</creatorcontrib><creatorcontrib>Min, Changwook</creatorcontrib><creatorcontrib>Kyoung, Dae-Sung</creatorcontrib><creatorcontrib>Park, Min-Ae</creatorcontrib><creatorcontrib>Kim, Sang Gyune</creatorcontrib><creatorcontrib>Kim, Young Seok</creatorcontrib><creatorcontrib>Chang, Young</creatorcontrib><creatorcontrib>Jeong, Soung Won</creatorcontrib><creatorcontrib>Jang, Jae Young</creatorcontrib><creatorcontrib>Lee, Sae Hwan</creatorcontrib><creatorcontrib>Kim, Hong Soo</creatorcontrib><creatorcontrib>Jun, Baek Gyu</creatorcontrib><creatorcontrib>Kim, Young Don</creatorcontrib><creatorcontrib>Cheon, Gab Jin</creatorcontrib><creatorcontrib>Yoo, Jeong-Ju</creatorcontrib><title>Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study</title><title>PloS one</title><description>We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56-1.79, P<0.001], especially in-hospital mortality. In liver cirrhosis group, presence of decompensation or varices showed significantly increased postoperative complication or mortality. Adverse outcomes in patients with cirrhosis was the highest in patients who underwent otorhinolaryngology surgery (aOR 1.86), followed by neurosurgery (aOR 1.72), thoracic and cardiovascular surgery (aOR 1.56), and plastic surgery (aOR 1.36). The adverse outcomes of patients with cirrhosis is significantly high after surgery, despite advances in cirrhosis treatment.</description><subject>Adverse events</subject><subject>Antiviral agents</subject><subject>Biology and Life Sciences</subject><subject>Chronic obstructive pulmonary disease</subject><subject>Cirrhosis</subject><subject>Codes</subject><subject>Complications and side effects</subject><subject>Disease</subject><subject>Fatty liver</subject><subject>Gastroenterology</subject><subject>Health insurance</subject><subject>Health risks</subject><subject>Hepatology</subject><subject>Hospitals</subject><subject>Internal medicine</subject><subject>Life expectancy</subject><subject>Life span</subject><subject>Liver</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Mortality</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Population</subject><subject>Population studies</subject><subject>Population-based studies</subject><subject>Prognosis</subject><subject>Regression analysis</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>Surgery</subject><subject>Variables</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk12L1DAUhoso7rr6DwQLgujFjPne1AthWPwYXFjw6zakyWknQ9uMSbq6_97MTpWp7IXkIjnJ874nOeQUxVOMlpie49dbP4ZBd8udH2CJCKdY8HvFKa4oWQiC6P2j9UnxKMYtQpxKIR4WJ5RhwqVAp0Vc2WsIEUo_JuN7iKVuEoQyjqGF4HLshnKnk4MhxfKnS5uyc1lRGhfCxkeXBb0f2vKTD6Az6ndjl3E_vClXR9Gi1hFsGdNobx4XDxrdRXgyzWfFt_fvvl58XFxefVhfrC4XRogqLTAVktXnAKgmlZFYEgZGG6Q5YpxQVFecM6MpxXVFOeaWWtRoCQ2jmFS6oWfFs4PvrvNRTfWKinCGzjEWTGZifSCs11u1C67X4UZ57dTthg-t0iE504GStjY0XwdJLphthIRaS8YwolYSy1D2ejtlG-serMkFC7qbmc5PBrdRrb9WkiBS8b3By8kg-B8jxKR6Fw10nR7Aj7f3xpRgzERGn_-D3v26iWp1foAbGp_zmr2pWgnBcSUIZZla3kHlYaF3Jn-uxuX9meDVTJCZBL9Sq8cY1frL5_9nr77P2RdH7AZ0lzbRd-P--8Q5yA6gCT7GAM3fImOk9r3xpxpq3xtq6g36G6iaAFM</recordid><startdate>20210614</startdate><enddate>20210614</enddate><creator>Jo, Hyun Ho</creator><creator>Min, Changwook</creator><creator>Kyoung, Dae-Sung</creator><creator>Park, Min-Ae</creator><creator>Kim, Sang Gyune</creator><creator>Kim, Young Seok</creator><creator>Chang, Young</creator><creator>Jeong, Soung Won</creator><creator>Jang, Jae Young</creator><creator>Lee, Sae Hwan</creator><creator>Kim, Hong Soo</creator><creator>Jun, Baek Gyu</creator><creator>Kim, Young Don</creator><creator>Cheon, Gab Jin</creator><creator>Yoo, Jeong-Ju</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-7113-3623</orcidid><orcidid>https://orcid.org/0000-0002-7802-0381</orcidid><orcidid>https://orcid.org/0000-0003-3993-716X</orcidid></search><sort><creationdate>20210614</creationdate><title>Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study</title><author>Jo, Hyun Ho ; Min, Changwook ; Kyoung, Dae-Sung ; Park, Min-Ae ; Kim, Sang Gyune ; Kim, Young Seok ; Chang, Young ; Jeong, Soung Won ; Jang, Jae Young ; Lee, Sae Hwan ; Kim, Hong Soo ; Jun, Baek Gyu ; Kim, Young Don ; Cheon, Gab Jin ; Yoo, Jeong-Ju</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c669t-13684b7ee0b29c81824ecac0a5045230b9554ca331b93515d3d0fa8ef43129af3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Adverse events</topic><topic>Antiviral agents</topic><topic>Biology and Life Sciences</topic><topic>Chronic obstructive pulmonary disease</topic><topic>Cirrhosis</topic><topic>Codes</topic><topic>Complications and side effects</topic><topic>Disease</topic><topic>Fatty liver</topic><topic>Gastroenterology</topic><topic>Health insurance</topic><topic>Health risks</topic><topic>Hepatology</topic><topic>Hospitals</topic><topic>Internal medicine</topic><topic>Life expectancy</topic><topic>Life span</topic><topic>Liver</topic><topic>Liver cirrhosis</topic><topic>Liver diseases</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Mortality</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Population</topic><topic>Population studies</topic><topic>Population-based studies</topic><topic>Prognosis</topic><topic>Regression analysis</topic><topic>Risk analysis</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Variables</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jo, Hyun Ho</creatorcontrib><creatorcontrib>Min, Changwook</creatorcontrib><creatorcontrib>Kyoung, Dae-Sung</creatorcontrib><creatorcontrib>Park, Min-Ae</creatorcontrib><creatorcontrib>Kim, Sang Gyune</creatorcontrib><creatorcontrib>Kim, Young Seok</creatorcontrib><creatorcontrib>Chang, Young</creatorcontrib><creatorcontrib>Jeong, Soung Won</creatorcontrib><creatorcontrib>Jang, Jae Young</creatorcontrib><creatorcontrib>Lee, Sae Hwan</creatorcontrib><creatorcontrib>Kim, Hong Soo</creatorcontrib><creatorcontrib>Jun, Baek Gyu</creatorcontrib><creatorcontrib>Kim, Young Don</creatorcontrib><creatorcontrib>Cheon, Gab Jin</creatorcontrib><creatorcontrib>Yoo, Jeong-Ju</creatorcontrib><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection (ProQuest)</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jo, Hyun Ho</au><au>Min, Changwook</au><au>Kyoung, Dae-Sung</au><au>Park, Min-Ae</au><au>Kim, Sang Gyune</au><au>Kim, Young Seok</au><au>Chang, Young</au><au>Jeong, Soung Won</au><au>Jang, Jae Young</au><au>Lee, Sae Hwan</au><au>Kim, Hong Soo</au><au>Jun, Baek Gyu</au><au>Kim, Young Don</au><au>Cheon, Gab Jin</au><au>Yoo, Jeong-Ju</au><au>Yeh, Chun Chieh</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study</atitle><jtitle>PloS one</jtitle><date>2021-06-14</date><risdate>2021</risdate><volume>16</volume><issue>6</issue><spage>e0253165</spage><epage>e0253165</epage><pages>e0253165-e0253165</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>We used the Health Insurance Review and Assessment Service-National Inpatient Samples (HIRA-NIS) between 2012 and 2016. In-hospital mortality and hospital stay were analyzed using the data. Mortality rates according to the surgical department were also analyzed. Of the 1,662,887 patients who underwent surgery, 16,174 (1.0%) patients had cirrhosis. The in-hospital mortality (8.0% vs. 1.0%) and postoperative complications such as respiratory (6.0% vs. 5.3%) or infections (2.8% vs. 2.4%) was significantly higher in patients with cirrhosis than in those without cirrhosis. In addition, the total hospitalization period and use of the intensive care unit were significantly higher in patients with liver cirrhosis. In propensity score matching analysis, liver cirrhosis increased the risk of adverse outcome significantly [adjusted OR (aOR) 1.67, 95% CI 1.56-1.79, P<0.001], especially in-hospital mortality. In liver cirrhosis group, presence of decompensation or varices showed significantly increased postoperative complication or mortality. Adverse outcomes in patients with cirrhosis was the highest in patients who underwent otorhinolaryngology surgery (aOR 1.86), followed by neurosurgery (aOR 1.72), thoracic and cardiovascular surgery (aOR 1.56), and plastic surgery (aOR 1.36). The adverse outcomes of patients with cirrhosis is significantly high after surgery, despite advances in cirrhosis treatment.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>34125860</pmid><doi>10.1371/journal.pone.0253165</doi><tpages>e0253165</tpages><orcidid>https://orcid.org/0000-0002-7113-3623</orcidid><orcidid>https://orcid.org/0000-0002-7802-0381</orcidid><orcidid>https://orcid.org/0000-0003-3993-716X</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2021-06, Vol.16 (6), p.e0253165-e0253165 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2540711648 |
| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Public Library of Science (PLoS); PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Adverse events Antiviral agents Biology and Life Sciences Chronic obstructive pulmonary disease Cirrhosis Codes Complications and side effects Disease Fatty liver Gastroenterology Health insurance Health risks Hepatology Hospitals Internal medicine Life expectancy Life span Liver Liver cirrhosis Liver diseases Medicine Medicine and Health Sciences Mortality Patient outcomes Patients Population Population studies Population-based studies Prognosis Regression analysis Risk analysis Risk factors Surgery Variables |
| title | Adverse outcomes after surgeries in patients with liver cirrhosis among Korean population: A population-based study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T10%3A21%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Adverse%20outcomes%20after%20surgeries%20in%20patients%20with%20liver%20cirrhosis%20among%20Korean%20population:%20A%20population-based%20study&rft.jtitle=PloS%20one&rft.au=Jo,%20Hyun%20Ho&rft.date=2021-06-14&rft.volume=16&rft.issue=6&rft.spage=e0253165&rft.epage=e0253165&rft.pages=e0253165-e0253165&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0253165&rft_dat=%3Cgale_plos_%3EA665196234%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2540711648&rft_id=info:pmid/34125860&rft_galeid=A665196234&rft_doaj_id=oai_doaj_org_article_8dbc34b708564df68eba844103d82d40&rfr_iscdi=true |