Integrated bioinformatics analysis and screening of hub genes in papillary thyroid carcinoma

With the increasing incidence of papillary thyroid carcinoma (PTC), PTC continues to garner attention worldwide; however its pathogenesis remains to be elucidated. The purpose of this study was to explore key biomarkers and potential new therapeutic targets for, PTC. GEO2R and Venn online software w...

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Veröffentlicht in:	PloS one 2021-06, Vol.16 (6), p.e0251962
Hauptverfasser:	Fan, Rong, Dong, Lijin, Li, Ping, Wang, Xiaoming, Chen, Xuewei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Binding Bioinformatics Biology and Life Sciences Biomarkers Biomarkers, Tumor - genetics Biotechnology industry Bone morphogenetic proteins Calcium Calcium ions Cancer Cancer therapies Care and treatment Cell adhesion Cell differentiation Cell migration Chemotherapy Computational biology Computational Biology - methods Computer and Information Sciences Datasets Diagnosis DNA-directed RNA polymerase Endothelial cells Engineering and Technology Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Ontology Gene Regulatory Networks Gene targeting Genetic aspects Genetic screening Glycoproteins Growth factors Health aspects Humans Iodine 131 Iodine radioisotopes Kinases MAP kinase Medical prognosis Medicine Medicine and Health Sciences Methods Morphogenesis Papillary thyroid carcinoma Peptidase Peptidases Physicians Prognosis Prostate cancer Protein Interaction Maps - genetics Protein-serine/threonine phosphatase Protein-tyrosine-phosphatase Proteins Receptors Receptors, Lysophosphatidic Acid - genetics Receptors, Lysophosphatidic Acid - metabolism Risk factors RNA polymerase RNA polymerase II Septum Signal transduction Signaling Smad protein Statistical analysis Survival Survival analysis Therapeutic targets Thyroid Thyroid cancer Thyroid Cancer, Papillary - genetics Thyroid Cancer, Papillary - pathology Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Transforming growth factor-b Tyrosine Ventricle
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