A new method for the study of biophysical and morphological parameters in 3D cell cultures: Evaluation in LoVo spheroids treated with crizotinib

Three-dimensional (3D) culture systems like tumor spheroids represent useful in vitro models for drug screening and more broadly for cancer biology research, but the generation of uniform populations of spheroids remains challenging. The possibility to properly characterize spheroid properties would...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2021-06, Vol.16 (6), p.e0252907-e0252907
Hauptverfasser:	Sargenti, Azzurra, Musmeci, Francesco, Cavallo, Carola, Mazzeschi, Martina, Bonetti, Simone, Pasqua, Simone, Bacchi, Francesco, Filardo, Giuseppe, Gazzola, Daniele, Lauriola, Mattia, Santi, Spartaco
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Biology and Life Sciences Bulk density Care and treatment Cell culture Colon Colon cancer Colorectal cancer Complications and side effects Computer programs Crizotinib Dynamics Editing Engineering and Technology Funding Genetics Inhibitor drugs Kinases Life sciences Mass transport Medicine Medicine and Health Sciences Morphology Patient outcomes Physical Sciences Proteins Research and Analysis Methods Research facilities Reviews Software Solid tumors Spheroids Targeted cancer therapy Three dimensional models Tumors Tyrosine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!