Association between toothbrushing and non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mech...
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| description | Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index [greater than or equal to]60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35-0.91) in the group who performed toothbrushing [greater than or equal to] 3 per day compared to the group that performed toothbrushing [less than or equal to] 1 per day. For those with toothbrushing frequency [less than or equal to]1 per day, the adjusted OR (95% CIs) of NAFLD was 2.26 (1.22-4.19) in smokers and 4.52 (1.97-10.38) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency [greater than or equal to]2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients. |
| doi_str_mv | 10.1371/journal.pone.0243686 |
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Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index [greater than or equal to]60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35-0.91) in the group who performed toothbrushing [greater than or equal to] 3 per day compared to the group that performed toothbrushing [less than or equal to] 1 per day. For those with toothbrushing frequency [less than or equal to]1 per day, the adjusted OR (95% CIs) of NAFLD was 2.26 (1.22-4.19) in smokers and 4.52 (1.97-10.38) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency [greater than or equal to]2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0243686</identifier><identifier>PMID: 34043630</identifier><language>eng</language><publisher>San Francisco: Public Library of Science</publisher><subject>Actuarial science ; Alcohol ; Alcohol use ; Biology and Life Sciences ; Cardiovascular disease ; Cholesterol ; Cirrhosis ; Complications and side effects ; Dentistry ; Diabetes ; Diabetes mellitus ; Disease control ; Editing ; Education ; Educational attainment ; Endocrinology ; Environmental health ; Epidemiology ; Exercise ; Family income ; Fasting ; Fatty liver ; Gum disease ; Health aspects ; Hepatocellular carcinoma ; Hospitals ; Households ; Liver ; Liver cirrhosis ; Liver diseases ; Maxillofacial ; Maxillofacial surgery ; Medical schools ; Medicine ; Medicine and Health Sciences ; Metabolic disorders ; Metabolic syndrome ; Nutrition ; Oral hygiene ; Periodontitis ; Physical fitness ; Questionnaires ; Reviews ; Risk analysis ; Risk factors ; Smoking ; Social Sciences ; Statistical analysis ; Surgery ; Toothbrushing</subject><ispartof>PloS one, 2021-05, Vol.16 (5), p.e0243686</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 Kim et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. 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Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index [greater than or equal to]60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35-0.91) in the group who performed toothbrushing [greater than or equal to] 3 per day compared to the group that performed toothbrushing [less than or equal to] 1 per day. For those with toothbrushing frequency [less than or equal to]1 per day, the adjusted OR (95% CIs) of NAFLD was 2.26 (1.22-4.19) in smokers and 4.52 (1.97-10.38) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency [greater than or equal to]2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients.</description><subject>Actuarial science</subject><subject>Alcohol</subject><subject>Alcohol use</subject><subject>Biology and Life Sciences</subject><subject>Cardiovascular disease</subject><subject>Cholesterol</subject><subject>Cirrhosis</subject><subject>Complications and side effects</subject><subject>Dentistry</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Disease control</subject><subject>Editing</subject><subject>Education</subject><subject>Educational attainment</subject><subject>Endocrinology</subject><subject>Environmental health</subject><subject>Epidemiology</subject><subject>Exercise</subject><subject>Family income</subject><subject>Fasting</subject><subject>Fatty liver</subject><subject>Gum disease</subject><subject>Health aspects</subject><subject>Hepatocellular 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between toothbrushing and non-alcoholic fatty liver disease</title><author>Kim, Ji-Youn ; Park, Yong-Moon ; Lee, Gyu-Na ; Song, Hyun Chul ; Ahn, Yu-Bae ; Han, Kyungdo ; Ko, Seung-Hyun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c665t-acaa48a6ce5785ec1bfca49498d890cc2d7b0211d4f81939ee1d47da6f31be0f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Actuarial science</topic><topic>Alcohol</topic><topic>Alcohol use</topic><topic>Biology and Life Sciences</topic><topic>Cardiovascular disease</topic><topic>Cholesterol</topic><topic>Cirrhosis</topic><topic>Complications and side effects</topic><topic>Dentistry</topic><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Disease control</topic><topic>Editing</topic><topic>Education</topic><topic>Educational attainment</topic><topic>Endocrinology</topic><topic>Environmental 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kim, Ji-Youn</au><au>Park, Yong-Moon</au><au>Lee, Gyu-Na</au><au>Song, Hyun Chul</au><au>Ahn, Yu-Bae</au><au>Han, Kyungdo</au><au>Ko, Seung-Hyun</au><au>Li, Houkai</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association between toothbrushing and non-alcoholic fatty liver disease</atitle><jtitle>PloS one</jtitle><date>2021-05-27</date><risdate>2021</risdate><volume>16</volume><issue>5</issue><spage>e0243686</spage><pages>e0243686-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index [greater than or equal to]60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35-0.91) in the group who performed toothbrushing [greater than or equal to] 3 per day compared to the group that performed toothbrushing [less than or equal to] 1 per day. For those with toothbrushing frequency [less than or equal to]1 per day, the adjusted OR (95% CIs) of NAFLD was 2.26 (1.22-4.19) in smokers and 4.52 (1.97-10.38) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency [greater than or equal to]2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients.</abstract><cop>San Francisco</cop><pub>Public Library of Science</pub><pmid>34043630</pmid><doi>10.1371/journal.pone.0243686</doi><tpages>e0243686</tpages><orcidid>https://orcid.org/0000-0003-3703-1479</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Actuarial science Alcohol Alcohol use Biology and Life Sciences Cardiovascular disease Cholesterol Cirrhosis Complications and side effects Dentistry Diabetes Diabetes mellitus Disease control Editing Education Educational attainment Endocrinology Environmental health Epidemiology Exercise Family income Fasting Fatty liver Gum disease Health aspects Hepatocellular carcinoma Hospitals Households Liver Liver cirrhosis Liver diseases Maxillofacial Maxillofacial surgery Medical schools Medicine Medicine and Health Sciences Metabolic disorders Metabolic syndrome Nutrition Oral hygiene Periodontitis Physical fitness Questionnaires Reviews Risk analysis Risk factors Smoking Social Sciences Statistical analysis Surgery Toothbrushing |
| title | Association between toothbrushing and non-alcoholic fatty liver disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T18%3A01%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Association%20between%20toothbrushing%20and%20non-alcoholic%20fatty%20liver%20disease&rft.jtitle=PloS%20one&rft.au=Kim,%20Ji-Youn&rft.date=2021-05-27&rft.volume=16&rft.issue=5&rft.spage=e0243686&rft.pages=e0243686-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0243686&rft_dat=%3Cgale_plos_%3EA663279439%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2533258348&rft_id=info:pmid/34043630&rft_galeid=A663279439&rft_doaj_id=oai_doaj_org_article_2d244d061c0a4033b7b93e27e74716f7&rfr_iscdi=true |