Increasing salinity of fibrinogen solvent generates stable fibrin hydrogels for cell delivery or tissue engineering

Fibrin has been used clinically for wound coverings, surgical glues, and cell delivery because of its affordability, cytocompatibility, and ability to modulate angiogenesis and inflammation. However, its rapid degradation rate has limited its usefulness as a scaffold for 3D cell culture and tissue e...

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Veröffentlicht in:	PloS one 2021-05, Vol.16 (5), p.e0239242-e0239242
Hauptverfasser:	Jarrell, Dillon K, Vanderslice, Ethan J, Lennon, Mallory L, Lyons, Anne C, VeDepo, Mitchell C, Jacot, Jeffrey G
Format:	Artikel
Sprache:	eng
Schlagworte:	Amniotic fluid Analysis Angiogenesis Biocompatibility Bioengineering Biological activity Biology and Life Sciences Cell culture Cell differentiation Data analysis Degradation Editing Engineering and Technology Fibrin Fibrinogen Fibrinolysis Fibroblasts Funding Gels Glues Hydrogels Inhibitors Measurement Morphology Pediatrics Physical Sciences Plasmin Polymerization Reviews Salinity Salt Stem cells Surgical implants Tissue engineering
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