Extracellular spreading of Wingless is required for Drosophila oogenesis

Recent studies have investigated whether the Wnt family of extracellular ligands can signal at long range, spreading from their source and acting as morphogens, or whether they signal only in a juxtacrine manner to neighboring cells. The original evidence for long-range Wnt signaling arose from stud...

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Veröffentlicht in:	PLoS genetics 2021-04, Vol.17 (4), p.e1009469-e1009469
Hauptverfasser:	Wang, Xiaoxi, LaFever, Kimberly S, Waghmare, Indrayani, Page-McCaw, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Analysis Animals Biology and Life Sciences Cell proliferation Cell Proliferation - genetics Chromosomes Drosophila Drosophila melanogaster - genetics Drosophila Proteins - genetics Female Females Fertility Genetic aspects Heparan sulfate proteoglycans Hybridization Insects Ligands Medicine and Health Sciences Membrane Glycoproteins - genetics Morphogenesis - genetics Oogenesis Oogenesis - genetics Ovarian Follicle - growth & development Phenotype Physiological aspects Proteins Research and analysis methods Spreading Stem cells Toxicity Transcription Wings, Animal - growth & development Wnt Proteins - genetics Wnt Signaling Pathway - genetics Wnt1 Protein - genetics
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