The effects of flavonoids, green tea polyphenols and coffee on DMBA induced LINE-1 DNA hypomethylation

The intake of carcinogenic and chemopreventive compounds are important nutritional factors related to the development of malignant tumorous diseases. Repetitive long interspersed element-1 (LINE-1) DNA methylation pattern plays a key role in both carcinogenesis and chemoprevention. In our present in...

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Veröffentlicht in:	PloS one 2021-04, Vol.16 (4), p.e0250157
Hauptverfasser:	Szabo, Laszlo, Molnar, Richard, Tomesz, Andras, Deutsch, Arpad, Darago, Richard, Nowrasteh, Ghodratollah, Varjas, Timea, Nemeth, Balazs, Budan, Ferenc, Kiss, Istvan
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Animal models Anthracene Anti-inflammatory agents Antioxidants Bioflavonoids Biological properties Biology and life sciences Biomarkers Camellia sinensis Carcinogenesis Carcinogens Catechin Cell cycle Cell growth Chemical properties Cocarcinogens Coffea arabica Coffee Cytochrome P450 Damage Deoxyribonucleic acid Diet DNA DNA methylation DNA methyltransferase Enzymes Epigenetics Experiments Flavones Flavonoids Free radicals Gene expression Genomes Glutathione Green tea Health aspects In vivo methods and tests Inflammation Kidneys Liver Medical schools Medicine Medicine and Health Sciences Methylation Morella rubra Organs Pharmacology, Experimental Polyphenols Public health Research and analysis methods Resveratrol Software Spleen Tea Transcription factors
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