The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

Mosquitoes are vectors of major diseases such as dengue fever and malaria. Mass drug administration of endectocides to humans and livestock is a promising complementary approach to current insecticide-based vector control measures. The aim of this study was to establish an insect model for pharmacok...

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Veröffentlicht in:	PLoS pathogens 2021-03, Vol.17 (3), p.e1009382
Hauptverfasser:	Duthaler, Urs, Weber, Michael, Hofer, Lorenz, Chaccour, Carlos, Maia, Marta, Müller, Pie, Krähenbühl, Stephan, Hammann, Felix
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome Aedes Aedes aegypti AIDS Analysis Aquatic insects Arthropods Biology and Life Sciences Blood Climate change Complications and side effects Culicidae Cytochrome Dengue Dengue fever Disease Disease control Drug dosages Drug interactions Estimates Insecticides Ivermectin Malaria Medicine and Health Sciences Model testing Mosquitoes Patient outcomes Pharmacokinetics Pharmacology Population Population studies Tropical diseases Tuberculosis Vector-borne diseases Viral diseases Viruses Yellow fever
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