Changes in both trans- and cis-regulatory elements mediate insecticide resistance in a lepidopteron pest, Spodoptera exigua

The evolution of insect resistance to insecticides is frequently associated with overexpression of one or more cytochrome P450 enzyme genes. Although overexpression of CYP450 genes is a well-known mechanism of insecticide resistance, the underlying regulatory mechanisms are poorly understood. Here w...

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Veröffentlicht in:	PLoS genetics 2021-03, Vol.17 (3), p.e1009403
Hauptverfasser:	Hu, Bo, Huang, He, Hu, Songzhu, Ren, Miaomiao, Wei, Qi, Tian, Xiangrui, Esmail Abdalla Elzaki, Mohammed, Bass, Chris, Su, Jianya, Reddy Palli, Subba
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Bioassays Biology and Life Sciences Cytochrome DNA Enzymatic activity Enzymes Gene regulation Genes Genetic aspects Insecticide resistance Insecticides Insects Lepidoptera Metabolism Molecular modelling Mortality Mutation Natural history Pesticide resistance Physiological aspects Proteins Regulatory sequences Research and Analysis Methods Transcription factors
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