Interspecies chimeric conditions affect the developmental rate of human pluripotent stem cells

Human pluripotent stem cells hold significant promise for regenerative medicine. However, long differentiation protocols and immature characteristics of stem cell-derived cell types remain challenges to the development of many therapeutic applications. In contrast to the slow differentiation of huma...

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Veröffentlicht in:	PLoS computational biology 2021-03, Vol.17 (3), p.e1008778-e1008778
Hauptverfasser:	Brown, Jared, Barry, Christopher, Schmitz, Matthew T, Argus, Cara, Bolin, Jennifer M, Schwartz, Michael P, Van Aartsen, Amy, Steill, John, Swanson, Scott, Stewart, Ron, Thomson, James A, Kendziorski, Christina
Format:	Artikel
Sprache:	eng
Schlagworte:	Biology and Life Sciences Cell culture Cell cycle Cell differentiation Comparative analysis Correlation analysis Data analysis Differentiation Gene expression Genetic aspects Identification and classification Methods Microscopy Neurogenesis Neurons Pluripotency Quality control Regenerative medicine Regression analysis Research and Analysis Methods Ribonucleic acid RNA Segmentation Stem cell research Stem cell transplantation Stem cells Transcriptomes Trends
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