Lymphatic endothelial-cell expressed ACKR3 is dispensable for postnatal lymphangiogenesis and lymphatic drainage function in mice

Atypical chemokine receptor ACKR3 (formerly CXCR7) is a scavenging receptor that has recently been implicated in murine lymphatic development. Specifically, ACKR3-deficiency was shown to result in lymphatic hyperplasia and lymphedema, in addition to cardiac hyperplasia and cardiac valve defects lead...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	PloS one 2021-04, Vol.16 (4), p.e0249068-e0249068
Hauptverfasser:	Sigmund, Elena C, Baur, Lilian, Schineis, Philipp, Arasa, Jorge, Collado-Diaz, Victor, Vranova, Martina, Stahl, Rolf A K, Thelen, Marcus, Halin, Cornelia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin Animals Biology and Life Sciences Blood Blood vessels Cancer Cell migration Cell proliferation Chemokine receptors Chemokines Cloning CXCL11 protein CXCL12 protein Editing Embryos Endothelial cells Endothelium Funding Gene expression Genetic aspects Hyperplasia Ligands Lymphatic diseases Lymphatic drainage Lymphatic system Lymphedema Medicine and Health Sciences Methodology Morphology Narcotics Opioid peptides Opioids Peptides Permeability Pharmaceutical sciences Pharmaceuticals Phenotypes Physiological aspects Prevention Receptors Research and Analysis Methods Reviews Scavenging Therapeutic targets Visualization Wound drainage
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!