Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study
The epidemiology of Interstitial Lung Diseases (ILD) in the Veterans Health Administration (VHA) is presently unknown. Describe the incidence/prevalence, clinical characteristics, and outcomes of ILD patients within the Veteran's Administration Mid-Atlantic Health Care Network (VISN6). A multi-...
Gespeichert in:
| Veröffentlicht in: | PloS one 2021-03, Vol.16 (3), p.e0247316-e0247316 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e0247316 |
|---|---|
| container_issue | 3 |
| container_start_page | e0247316 |
| container_title | PloS one |
| container_volume | 16 |
| creator | Bedoya, Armando Pleasants, Roy A Boggan, Joel C Seaman, Danielle Reihman, Anne Howard, Lauren Kundich, Robert Welty-Wolf, Karen Tighe, Robert M |
| description | The epidemiology of Interstitial Lung Diseases (ILD) in the Veterans Health Administration (VHA) is presently unknown.
Describe the incidence/prevalence, clinical characteristics, and outcomes of ILD patients within the Veteran's Administration Mid-Atlantic Health Care Network (VISN6).
A multi-center retrospective cohort study was performed of veterans receiving hospital or outpatient ILD care from January 1, 2008 to December 31st, 2015 in six VISN6 facilities. Patients were identified by at least one visit encounter with a 515, 516, or other ILD ICD-9 code. Demographic and clinical characteristics were summarized using median, 25th and 75th percentile for continuous variables and count/percentage for categorical variables. Characteristics and incidence/prevalence rates were summarized, and stratified by ILD ICD-9 code. Kaplan Meier curves were generated to define overall survival.
3293 subjects met the inclusion criteria. 879 subjects (26%) had no evidence of ILD following manual medical record review. Overall estimated prevalence in verified ILD subjects was 256 per 100,000 people with a mean incidence across the years of 70 per 100,000 person-years (0.07%). The prevalence and mean incidence when focusing on people with an ILD diagnostic code who had a HRCT scan or a bronchoscopic or surgical lung biopsy was 237 per 100,000 people (0.237%) and 63 per 100,000 person-years respectively (0.063%). The median survival was 76.9 months for 515 codes, 103.4 months for 516 codes, and 83.6 months for 516.31.
This retrospective cohort study defines high ILD incidence/prevalence within the VA. Therefore, ILD is an important VA health concern. |
| doi_str_mv | 10.1371/journal.pone.0247316 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_2502782196</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A655465738</galeid><doaj_id>oai_doaj_org_article_d21d0e79dbba4624a56030cc4a4f2cd1</doaj_id><sourcerecordid>A655465738</sourcerecordid><originalsourceid>FETCH-LOGICAL-c692t-7d7f2f8a4e005b68fde5b65cd35138c35aec62003f0e36b4fce5ac0e37617ca63</originalsourceid><addsrcrecordid>eNqNk1trFDEUxwdRbK1-A9EBQfRh12SSSXYRhFK8LBQK3h4NZ5OT2dTZyZpkVvvtzXanZUf6IHlISH7nfy45pyieUjKlTNI3l74PHbTTje9wSiouGRX3imM6Z9VEVITdPzgfFY9ivCSkZjMhHhZHjElWZ5Pj4seiSxhicslBW7Z915TGRYSIpetKKLeYn6GLJVgLLsQyYON89lt2mH778PNthgKm4OMGdXJbLLVf-ZDKmHpz9bh4YKGN-GTYT4pvH95_Pfs0Ob_4uDg7PZ9oMa_SRBppKzsDjjnGpZhZg3mrtWE1ZTPNakCd8yDMEmRiya3GGnQ-S0GlBsFOiud73U3roxpKE1VVk0rOKjrfEYs9YTxcqk1wawhXyoNT1xc-NApCcrpFZSpqCMq5WS6Bi4pDLQgjWnPgttKGZq13g7d-uUajsUsB2pHo-KVzK9X4rZJzSbncBfNqEAj-V48xqbWLGtsWOvT9ddyMc5F9Z_TFP-jd2Q1UAzkB11mf_eqdqDoVdc1FLdksU9M7qLwMrp3OfWRdvh8ZvB4ZZCbhn9RAH6NafPn8_-zF9zH78oBdIbRpFX3bp9xacQzyPahzg8WA9rbIlKjdGNxUQ-3GQA1jkM2eHX7QrdFN37O_YsUD5A</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2502782196</pqid></control><display><type>article</type><title>Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study</title><source>DOAJ Directory of Open Access Journals</source><source>Public Library of Science (PLoS)</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><creator>Bedoya, Armando ; Pleasants, Roy A ; Boggan, Joel C ; Seaman, Danielle ; Reihman, Anne ; Howard, Lauren ; Kundich, Robert ; Welty-Wolf, Karen ; Tighe, Robert M</creator><contributor>Arjomandi, Mehrdad</contributor><creatorcontrib>Bedoya, Armando ; Pleasants, Roy A ; Boggan, Joel C ; Seaman, Danielle ; Reihman, Anne ; Howard, Lauren ; Kundich, Robert ; Welty-Wolf, Karen ; Tighe, Robert M ; Arjomandi, Mehrdad</creatorcontrib><description>The epidemiology of Interstitial Lung Diseases (ILD) in the Veterans Health Administration (VHA) is presently unknown.
Describe the incidence/prevalence, clinical characteristics, and outcomes of ILD patients within the Veteran's Administration Mid-Atlantic Health Care Network (VISN6).
A multi-center retrospective cohort study was performed of veterans receiving hospital or outpatient ILD care from January 1, 2008 to December 31st, 2015 in six VISN6 facilities. Patients were identified by at least one visit encounter with a 515, 516, or other ILD ICD-9 code. Demographic and clinical characteristics were summarized using median, 25th and 75th percentile for continuous variables and count/percentage for categorical variables. Characteristics and incidence/prevalence rates were summarized, and stratified by ILD ICD-9 code. Kaplan Meier curves were generated to define overall survival.
3293 subjects met the inclusion criteria. 879 subjects (26%) had no evidence of ILD following manual medical record review. Overall estimated prevalence in verified ILD subjects was 256 per 100,000 people with a mean incidence across the years of 70 per 100,000 person-years (0.07%). The prevalence and mean incidence when focusing on people with an ILD diagnostic code who had a HRCT scan or a bronchoscopic or surgical lung biopsy was 237 per 100,000 people (0.237%) and 63 per 100,000 person-years respectively (0.063%). The median survival was 76.9 months for 515 codes, 103.4 months for 516 codes, and 83.6 months for 516.31.
This retrospective cohort study defines high ILD incidence/prevalence within the VA. Therefore, ILD is an important VA health concern.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0247316</identifier><identifier>PMID: 33735247</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Bioinformatics ; Biology and Life Sciences ; Biopsy ; Bronchoscopy ; Codes ; Cohort analysis ; Computed tomography ; Computer and Information Sciences ; Data analysis ; Demographic aspects ; Demography ; Diagnosis ; Disease ; Drug therapy ; Editing ; Epidemiology ; Fibroblasts ; Fibrosis ; Funding ; Health aspects ; Health care facilities ; Immune system ; Lung diseases ; Lung diseases, Interstitial ; Medical diagnosis ; Medical imaging ; Medicine ; Medicine and Health Sciences ; Mortality ; Patient outcomes ; Patients ; Pulmonary functions ; Radiographs ; Radiography ; Radiology ; Respiratory diseases ; Respiratory function ; Thorax ; Veterans ; Visualization</subject><ispartof>PloS one, 2021-03, Vol.16 (3), p.e0247316-e0247316</ispartof><rights>COPYRIGHT 2021 Public Library of Science</rights><rights>2021 Bedoya et al. This is an open access article distributed under the terms of the Creative Commons Attribution License: http://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 Bedoya et al 2021 Bedoya et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c692t-7d7f2f8a4e005b68fde5b65cd35138c35aec62003f0e36b4fce5ac0e37617ca63</citedby><cites>FETCH-LOGICAL-c692t-7d7f2f8a4e005b68fde5b65cd35138c35aec62003f0e36b4fce5ac0e37617ca63</cites><orcidid>0000-0002-3465-9861</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971476/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7971476/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,2100,2919,23857,27915,27916,53782,53784,79361,79362</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/33735247$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Arjomandi, Mehrdad</contributor><creatorcontrib>Bedoya, Armando</creatorcontrib><creatorcontrib>Pleasants, Roy A</creatorcontrib><creatorcontrib>Boggan, Joel C</creatorcontrib><creatorcontrib>Seaman, Danielle</creatorcontrib><creatorcontrib>Reihman, Anne</creatorcontrib><creatorcontrib>Howard, Lauren</creatorcontrib><creatorcontrib>Kundich, Robert</creatorcontrib><creatorcontrib>Welty-Wolf, Karen</creatorcontrib><creatorcontrib>Tighe, Robert M</creatorcontrib><title>Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The epidemiology of Interstitial Lung Diseases (ILD) in the Veterans Health Administration (VHA) is presently unknown.
Describe the incidence/prevalence, clinical characteristics, and outcomes of ILD patients within the Veteran's Administration Mid-Atlantic Health Care Network (VISN6).
A multi-center retrospective cohort study was performed of veterans receiving hospital or outpatient ILD care from January 1, 2008 to December 31st, 2015 in six VISN6 facilities. Patients were identified by at least one visit encounter with a 515, 516, or other ILD ICD-9 code. Demographic and clinical characteristics were summarized using median, 25th and 75th percentile for continuous variables and count/percentage for categorical variables. Characteristics and incidence/prevalence rates were summarized, and stratified by ILD ICD-9 code. Kaplan Meier curves were generated to define overall survival.
3293 subjects met the inclusion criteria. 879 subjects (26%) had no evidence of ILD following manual medical record review. Overall estimated prevalence in verified ILD subjects was 256 per 100,000 people with a mean incidence across the years of 70 per 100,000 person-years (0.07%). The prevalence and mean incidence when focusing on people with an ILD diagnostic code who had a HRCT scan or a bronchoscopic or surgical lung biopsy was 237 per 100,000 people (0.237%) and 63 per 100,000 person-years respectively (0.063%). The median survival was 76.9 months for 515 codes, 103.4 months for 516 codes, and 83.6 months for 516.31.
This retrospective cohort study defines high ILD incidence/prevalence within the VA. Therefore, ILD is an important VA health concern.</description><subject>Bioinformatics</subject><subject>Biology and Life Sciences</subject><subject>Biopsy</subject><subject>Bronchoscopy</subject><subject>Codes</subject><subject>Cohort analysis</subject><subject>Computed tomography</subject><subject>Computer and Information Sciences</subject><subject>Data analysis</subject><subject>Demographic aspects</subject><subject>Demography</subject><subject>Diagnosis</subject><subject>Disease</subject><subject>Drug therapy</subject><subject>Editing</subject><subject>Epidemiology</subject><subject>Fibroblasts</subject><subject>Fibrosis</subject><subject>Funding</subject><subject>Health aspects</subject><subject>Health care facilities</subject><subject>Immune system</subject><subject>Lung diseases</subject><subject>Lung diseases, Interstitial</subject><subject>Medical diagnosis</subject><subject>Medical imaging</subject><subject>Medicine</subject><subject>Medicine and Health Sciences</subject><subject>Mortality</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Pulmonary functions</subject><subject>Radiographs</subject><subject>Radiography</subject><subject>Radiology</subject><subject>Respiratory diseases</subject><subject>Respiratory function</subject><subject>Thorax</subject><subject>Veterans</subject><subject>Visualization</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>DOA</sourceid><recordid>eNqNk1trFDEUxwdRbK1-A9EBQfRh12SSSXYRhFK8LBQK3h4NZ5OT2dTZyZpkVvvtzXanZUf6IHlISH7nfy45pyieUjKlTNI3l74PHbTTje9wSiouGRX3imM6Z9VEVITdPzgfFY9ivCSkZjMhHhZHjElWZ5Pj4seiSxhicslBW7Z915TGRYSIpetKKLeYn6GLJVgLLsQyYON89lt2mH778PNthgKm4OMGdXJbLLVf-ZDKmHpz9bh4YKGN-GTYT4pvH95_Pfs0Ob_4uDg7PZ9oMa_SRBppKzsDjjnGpZhZg3mrtWE1ZTPNakCd8yDMEmRiya3GGnQ-S0GlBsFOiud73U3roxpKE1VVk0rOKjrfEYs9YTxcqk1wawhXyoNT1xc-NApCcrpFZSpqCMq5WS6Bi4pDLQgjWnPgttKGZq13g7d-uUajsUsB2pHo-KVzK9X4rZJzSbncBfNqEAj-V48xqbWLGtsWOvT9ddyMc5F9Z_TFP-jd2Q1UAzkB11mf_eqdqDoVdc1FLdksU9M7qLwMrp3OfWRdvh8ZvB4ZZCbhn9RAH6NafPn8_-zF9zH78oBdIbRpFX3bp9xacQzyPahzg8WA9rbIlKjdGNxUQ-3GQA1jkM2eHX7QrdFN37O_YsUD5A</recordid><startdate>20210318</startdate><enddate>20210318</enddate><creator>Bedoya, Armando</creator><creator>Pleasants, Roy A</creator><creator>Boggan, Joel C</creator><creator>Seaman, Danielle</creator><creator>Reihman, Anne</creator><creator>Howard, Lauren</creator><creator>Kundich, Robert</creator><creator>Welty-Wolf, Karen</creator><creator>Tighe, Robert M</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-3465-9861</orcidid></search><sort><creationdate>20210318</creationdate><title>Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study</title><author>Bedoya, Armando ; Pleasants, Roy A ; Boggan, Joel C ; Seaman, Danielle ; Reihman, Anne ; Howard, Lauren ; Kundich, Robert ; Welty-Wolf, Karen ; Tighe, Robert M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c692t-7d7f2f8a4e005b68fde5b65cd35138c35aec62003f0e36b4fce5ac0e37617ca63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Bioinformatics</topic><topic>Biology and Life Sciences</topic><topic>Biopsy</topic><topic>Bronchoscopy</topic><topic>Codes</topic><topic>Cohort analysis</topic><topic>Computed tomography</topic><topic>Computer and Information Sciences</topic><topic>Data analysis</topic><topic>Demographic aspects</topic><topic>Demography</topic><topic>Diagnosis</topic><topic>Disease</topic><topic>Drug therapy</topic><topic>Editing</topic><topic>Epidemiology</topic><topic>Fibroblasts</topic><topic>Fibrosis</topic><topic>Funding</topic><topic>Health aspects</topic><topic>Health care facilities</topic><topic>Immune system</topic><topic>Lung diseases</topic><topic>Lung diseases, Interstitial</topic><topic>Medical diagnosis</topic><topic>Medical imaging</topic><topic>Medicine</topic><topic>Medicine and Health Sciences</topic><topic>Mortality</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Pulmonary functions</topic><topic>Radiographs</topic><topic>Radiography</topic><topic>Radiology</topic><topic>Respiratory diseases</topic><topic>Respiratory function</topic><topic>Thorax</topic><topic>Veterans</topic><topic>Visualization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bedoya, Armando</creatorcontrib><creatorcontrib>Pleasants, Roy A</creatorcontrib><creatorcontrib>Boggan, Joel C</creatorcontrib><creatorcontrib>Seaman, Danielle</creatorcontrib><creatorcontrib>Reihman, Anne</creatorcontrib><creatorcontrib>Howard, Lauren</creatorcontrib><creatorcontrib>Kundich, Robert</creatorcontrib><creatorcontrib>Welty-Wolf, Karen</creatorcontrib><creatorcontrib>Tighe, Robert M</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological & Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection (ProQuest)</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Meteorological & Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bedoya, Armando</au><au>Pleasants, Roy A</au><au>Boggan, Joel C</au><au>Seaman, Danielle</au><au>Reihman, Anne</au><au>Howard, Lauren</au><au>Kundich, Robert</au><au>Welty-Wolf, Karen</au><au>Tighe, Robert M</au><au>Arjomandi, Mehrdad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2021-03-18</date><risdate>2021</risdate><volume>16</volume><issue>3</issue><spage>e0247316</spage><epage>e0247316</epage><pages>e0247316-e0247316</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The epidemiology of Interstitial Lung Diseases (ILD) in the Veterans Health Administration (VHA) is presently unknown.
Describe the incidence/prevalence, clinical characteristics, and outcomes of ILD patients within the Veteran's Administration Mid-Atlantic Health Care Network (VISN6).
A multi-center retrospective cohort study was performed of veterans receiving hospital or outpatient ILD care from January 1, 2008 to December 31st, 2015 in six VISN6 facilities. Patients were identified by at least one visit encounter with a 515, 516, or other ILD ICD-9 code. Demographic and clinical characteristics were summarized using median, 25th and 75th percentile for continuous variables and count/percentage for categorical variables. Characteristics and incidence/prevalence rates were summarized, and stratified by ILD ICD-9 code. Kaplan Meier curves were generated to define overall survival.
3293 subjects met the inclusion criteria. 879 subjects (26%) had no evidence of ILD following manual medical record review. Overall estimated prevalence in verified ILD subjects was 256 per 100,000 people with a mean incidence across the years of 70 per 100,000 person-years (0.07%). The prevalence and mean incidence when focusing on people with an ILD diagnostic code who had a HRCT scan or a bronchoscopic or surgical lung biopsy was 237 per 100,000 people (0.237%) and 63 per 100,000 person-years respectively (0.063%). The median survival was 76.9 months for 515 codes, 103.4 months for 516 codes, and 83.6 months for 516.31.
This retrospective cohort study defines high ILD incidence/prevalence within the VA. Therefore, ILD is an important VA health concern.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>33735247</pmid><doi>10.1371/journal.pone.0247316</doi><tpages>e0247316</tpages><orcidid>https://orcid.org/0000-0002-3465-9861</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1932-6203 |
| ispartof | PloS one, 2021-03, Vol.16 (3), p.e0247316-e0247316 |
| issn | 1932-6203 1932-6203 |
| language | eng |
| recordid | cdi_plos_journals_2502782196 |
| source | DOAJ Directory of Open Access Journals; Public Library of Science (PLoS); EZB-FREE-00999 freely available EZB journals; PubMed Central; Free Full-Text Journals in Chemistry |
| subjects | Bioinformatics Biology and Life Sciences Biopsy Bronchoscopy Codes Cohort analysis Computed tomography Computer and Information Sciences Data analysis Demographic aspects Demography Diagnosis Disease Drug therapy Editing Epidemiology Fibroblasts Fibrosis Funding Health aspects Health care facilities Immune system Lung diseases Lung diseases, Interstitial Medical diagnosis Medical imaging Medicine Medicine and Health Sciences Mortality Patient outcomes Patients Pulmonary functions Radiographs Radiography Radiology Respiratory diseases Respiratory function Thorax Veterans Visualization |
| title | Interstitial lung disease in a veterans affairs regional network; a retrospective cohort study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-15T01%3A31%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Interstitial%20lung%20disease%20in%20a%20veterans%20affairs%20regional%20network;%20a%20retrospective%20cohort%20study&rft.jtitle=PloS%20one&rft.au=Bedoya,%20Armando&rft.date=2021-03-18&rft.volume=16&rft.issue=3&rft.spage=e0247316&rft.epage=e0247316&rft.pages=e0247316-e0247316&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0247316&rft_dat=%3Cgale_plos_%3EA655465738%3C/gale_plos_%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2502782196&rft_id=info:pmid/33735247&rft_galeid=A655465738&rft_doaj_id=oai_doaj_org_article_d21d0e79dbba4624a56030cc4a4f2cd1&rfr_iscdi=true |