New insights into the interactions between Blastocystis, the gut microbiota, and host immunity
The human gut microbiota is a diverse and complex ecosystem that is involved in beneficial physiological functions as well as disease pathogenesis. Blastocystis is a common protistan parasite and is increasingly recognized as an important component of the gut microbiota. The correlations between Bla...
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| Veröffentlicht in: | PLoS pathogens 2021-02, Vol.17 (2), p.e1009253-e1009253 |
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| creator | Deng, Lei Wojciech, Lukasz Gascoigne, Nicholas R J Peng, Guangneng Tan, Kevin S W |
| description | The human gut microbiota is a diverse and complex ecosystem that is involved in beneficial physiological functions as well as disease pathogenesis. Blastocystis is a common protistan parasite and is increasingly recognized as an important component of the gut microbiota. The correlations between Blastocystis and other communities of intestinal microbiota have been investigated, and, to a lesser extent, the role of this parasite in maintaining the host immunological homeostasis. Despite recent studies suggesting that Blastocystis decreases the abundance of beneficial bacteria, most reports indicate that Blastocystis is a common component of the healthy gut microbiome. This review covers recent finding on the potential interactions between Blastocystis and the gut microbiota communities and its roles in regulating host immune responses. |
| doi_str_mv | 10.1371/journal.ppat.1009253 |
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Blastocystis is a common protistan parasite and is increasingly recognized as an important component of the gut microbiota. The correlations between Blastocystis and other communities of intestinal microbiota have been investigated, and, to a lesser extent, the role of this parasite in maintaining the host immunological homeostasis. Despite recent studies suggesting that Blastocystis decreases the abundance of beneficial bacteria, most reports indicate that Blastocystis is a common component of the healthy gut microbiome. This review covers recent finding on the potential interactions between Blastocystis and the gut microbiota communities and its roles in regulating host immune responses.</description><identifier>ISSN: 1553-7374</identifier><identifier>ISSN: 1553-7366</identifier><identifier>EISSN: 1553-7374</identifier><identifier>DOI: 10.1371/journal.ppat.1009253</identifier><identifier>PMID: 33630979</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Abundance ; Animal models ; Bacteria ; Bacteroides ; Biology and Life Sciences ; Blastocystis ; Colonization ; Composition ; Digestive system ; Digestive tract ; Drug resistance ; Etiology ; Fatty acids ; Feces ; Flora ; Gastrointestinal tract ; Inflammatory bowel disease ; Intestinal microflora ; Intestine ; Irritable bowel syndrome ; Medicine and Health Sciences ; Metabolic disorders ; Metagenomics ; Microbiota ; Parasites ; Prevotella ; Relative abundance ; Review ; rRNA 16S ; rRNA 18S</subject><ispartof>PLoS pathogens, 2021-02, Vol.17 (2), p.e1009253-e1009253</ispartof><rights>2021 Deng et al. 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| subjects | Abundance Animal models Bacteria Bacteroides Biology and Life Sciences Blastocystis Colonization Composition Digestive system Digestive tract Drug resistance Etiology Fatty acids Feces Flora Gastrointestinal tract Inflammatory bowel disease Intestinal microflora Intestine Irritable bowel syndrome Medicine and Health Sciences Metabolic disorders Metagenomics Microbiota Parasites Prevotella Relative abundance Review rRNA 16S rRNA 18S |
| title | New insights into the interactions between Blastocystis, the gut microbiota, and host immunity |
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