Evidence for distinct mechanisms of small molecule inhibitors of filovirus entry

Many small molecules have been identified as entry inhibitors of filoviruses. However, a lack of understanding of the mechanism of action for these molecules limits further their development as anti-filoviral agents. Here we provide evidence that toremifene and other small molecule entry inhibitors...

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Veröffentlicht in:PLoS pathogens 2021-02, Vol.17 (2), p.e1009312-e1009312
Hauptverfasser: Schafer, Adam, Xiong, Rui, Cooper, Laura, Nowar, Raghad, Lee, Hyun, Li, Yangfeng, Ramirez, Benjamin E, Peet, Norton P, Caffrey, Michael, Thatcher, Gregory R J, Saphire, Erica Ollmann, Cheng, Han, Rong, Lijun
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Sprache:eng
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