Independent component analysis recovers consistent regulatory signals from disparate datasets

The availability of bacterial transcriptomes has dramatically increased in recent years. This data deluge could result in detailed inference of underlying regulatory networks, but the diversity of experimental platforms and protocols introduces critical biases that could hinder scalable analysis of...

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Veröffentlicht in:PLoS computational biology 2021-02, Vol.17 (2), p.e1008647-e1008647
Hauptverfasser: Sastry, Anand V, Hu, Alyssa, Heckmann, David, Poudel, Saugat, Kavvas, Erol, Palsson, Bernhard O
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Sprache:eng
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