Evolutionary analyses of the major variant surface antigen-encoding genes reveal population structure of Plasmodium falciparum within and between continents

Malaria remains a major public health problem in many countries. Unlike influenza and HIV, where diversity in immunodominant surface antigens is understood geographically to inform disease surveillance, relatively little is known about the global population structure of PfEMP1, the major variant sur...

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Veröffentlicht in:PLoS genetics 2021-02, Vol.17 (2), p.e1009269-e1009269
Hauptverfasser: Tonkin-Hill, Gerry, Ruybal-Pesántez, Shazia, Tiedje, Kathryn E, Rougeron, Virginie, Duffy, Michael F, Zakeri, Sedigheh, Pumpaibool, Tepanata, Harnyuttanakorn, Pongchai, Branch, OraLee H, Ruiz-Mesía, Lastenia, Rask, Thomas S, Prugnolle, Franck, Papenfuss, Anthony T, Chan, Yao-Ban, Day, Karen P
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Sprache:eng
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