A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

A diverse and abundant gut microbiome can improve cancer patients' treatment response; however, the effect of pelvic chemoradiotherapy (CRT) on gut diversity and composition is unclear. The purpose of this prospective study was to identify changes in the diversity and composition of the gut mic...

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Veröffentlicht in:	PloS one 2021-03, Vol.16 (3), p.e0247905
Hauptverfasser:	El Alam, Molly B, Sims, Travis T, Kouzy, Ramez, Biegert, Greyson W G, Jaoude, Joseph A B I, Karpinets, Tatiana V, Yoshida-Court, Kyoko, Wu, Xiaogang, Delgado-Medrano, Andrea Y, Mezzari, Melissa P, Ajami, Nadim J, Solley, Travis, Ahmed-Kaddar, Mustapha, Lin, Lilie L, Ramondetta, Lois, Jazaeri, Amir, Jhingran, Anuja, Eifel, Patricia J, Schmeler, Kathleen M, Wargo, Jennifer, Klopp, Ann H, Colbert, Lauren E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Auroral kilometric radiation Biology and Life Sciences Biomarkers Brachytherapy Cancer Cancer therapies Care and treatment Cervix Chemoradiotherapy Chemotherapy Complications and side effects Data analysis Digestive system Drug dosages Ecology and Environmental Sciences Editing Endometrial cancer Endometrium Funding Genetic aspects Genital cancer Genomics Human papillomavirus Immunotherapy Intestinal microflora Medical records Medicine Medicine and Health Sciences Metagenomics Methodology Microbiology Microbiomes Microbiota Microbiota (Symbiotic organisms) Mucosa Oncology Patients Physiological aspects Prostate cancer Protocol (computers) Radiation Radiation therapy Rectum Reproductive health Standard of care Tumors Visualization
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