Characterization and trypanocidal activity of a β-lapachone-containing drug carrier

The treatment of Chagas disease (CD), a neglected parasitic condition caused by Trypanosoma cruzi, is still based on only two drugs, nifurtimox (Nif) and benznidazole (Bz), both of which have limited efficacy in the late chronic phase and induce severe side effects. This scenario justifies the conti...

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Veröffentlicht in:PloS one 2021-03, Vol.16 (3), p.e0246811-e0246811
Hauptverfasser: Barbosa, Juliana M C, Nicoletti, Caroline D, da Silva, Patrícia B, Melo, Tatiana G, Futuro, Débora O, Ferreira, Vitor F, Salomão, Kelly
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Sprache:eng
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