Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers

The TSA Opal multiplex immunohistochemistry (mIHC) protocol (PerkinElmer) has been used to characterize immune infiltration in human cancers. This technique allows multiple biomarkers to be simultaneously stained in a single tissue section, which helps to elucidate the spatial relationship among ind...

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Veröffentlicht in:PloS one 2021-02, Vol.16 (2), p.e0247238-e0247238
Hauptverfasser: Sun, Zhaoyu, Nyberg, Richard, Wu, Yaping, Bernard, Brady, Redmond, William L
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Sprache:eng
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