Comparative efficacy and safety of pharmacological interventions for the treatment of COVID-19: A systematic review and network meta-analysis

Numerous clinical trials and observational studies have investigated various pharmacological agents as potential treatment for Coronavirus Disease 2019 (COVID-19), but the results are heterogeneous and sometimes even contradictory to one another, making it difficult for clinicians to determine which...

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Veröffentlicht in:	PLoS medicine 2020-12, Vol.17 (12), p.e1003501
Hauptverfasser:	Kim, Min Seo, An, Min Ho, Kim, Won Jun, Hwang, Tae-Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Monophosphate - adverse effects Adenosine Monophosphate - analogs & derivatives Adenosine Monophosphate - therapeutic use Adverse events Alanine - adverse effects Alanine - analogs & derivatives Alanine - therapeutic use Anti-Inflammatory Agents - adverse effects Anti-Inflammatory Agents - therapeutic use Azithromycin - adverse effects Azithromycin - therapeutic use Bias Biology and Life Sciences Clinical trials Comparative analysis Coronaviruses COVID-19 COVID-19 - mortality COVID-19 - therapy COVID-19 Drug Treatment COVID-19 Serotherapy Critical Illness Drug discovery Heart rate Hospitalization Humans Hydroxychloroquine - adverse effects Hydroxychloroquine - therapeutic use Immunization, Passive Intensive care Maximum likelihood method Mechanical ventilation Medicine and Health Sciences Meta-analysis Mortality Network Meta-Analysis Observational studies Observational Studies as Topic Patients Physical Sciences Randomized Controlled Trials as Topic Research and Analysis Methods Safety and security measures Treatment outcome Ventilation Ventilators
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