Potential applicability of cytokines as biomarkers of disease activity in rheumatoid arthritis: Enzyme-linked immunosorbent spot assay-based evaluation of TNF-α, IL-1β, IL-10 and IL-17A

Biomarkers play a pivotal role in the management of rheumatoid arthritis (RA) by facilitating early diagnosis and 'treat to the target.' However, no gold standard biomarker has been identified for monitoring the disease activity in RA. Cytokines, a diverse group of small protein molecules...

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Veröffentlicht in:	PloS one 2021-01, Vol.16 (1), p.e0246111-e0246111
Hauptverfasser:	Dissanayake, Keerthie, Jayasinghe, Chandrika, Wanigasekara, Priyani, Sominanda, Ajith
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Arthritis Bioassays Biology and Life Sciences Biomarkers C-reactive protein Chronic infection Citrulline Cytokines Erythrocyte sedimentation rate Erythrocytes Fibrinogen IL-1β Interleukin 10 Medicine Medicine and Health Sciences Methotrexate Patients Physical Sciences Prednisolone Remission Research and Analysis Methods Rheumatoid arthritis Rheumatoid factor Rheumatology Sampling methods Sampling techniques Signs and symptoms Steroid hormones Steroids Teaching hospitals Tumor necrosis factor-α
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