Differential expression of αVβ3 and αVβ6 integrins in prostate cancer progression

Neuroendocrine prostate cancer (NEPrCa) arises de novo or after accumulation of genomic alterations in pre-existing adenocarcinoma tumors in response to androgen deprivation therapies. We have provided evidence that small extracellular vesicles released by PrCa cells and containing the αVβ3 integrin...

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Veröffentlicht in:	PloS one 2021, Vol.16 (1), p.e0244985-e0244985
Hauptverfasser:	Quaglia, Fabio, Krishn, Shiv Ram, Wang, Yanqing, Goodrich, David W, McCue, Peter, Kossenkov, Andrew V, Mandigo, Amy C, Knudsen, Karen E, Weinreb, Paul H, Corey, Eva, Kelly, William K, Languino, Lucia R
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Animals Antigens, Neoplasm - metabolism Biology Biology and Life Sciences Cancer Cell adhesion & migration Cell Line, Tumor Computer applications COVID-19 Data analysis Deregulation Disease Models, Animal Disease Progression Editing Engineering and Technology Extracellular matrix Funding Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Integrin alphaVbeta3 - metabolism Integrins Integrins - metabolism Kinases Male Medicine and Health Sciences Metastasis Mice Mice, Nude Mice, Transgenic Monoclonal antibodies Neoplasm Transplantation Pharmacology Prostate Prostate - metabolism Prostate - pathology Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology PTEN protein Research and Analysis Methods Retinoblastoma Protein - genetics Reviews Severe acute respiratory syndrome coronavirus 2 Spike protein Synaptophysin - metabolism Tumor Suppressor Protein p53 - genetics Tumors Urology Viruses
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