The risk of adverse clinical outcomes following treatment of Plasmodium vivax malaria with and without primaquine in Papua, Indonesia

The widespread use of primaquine (PQ) radical cure for P. vivax, is constrained by concerns over its safety. We used routinely collected patient data to compare the overall morbidity and mortality in patients treated with and without PQ without prior testing of Glucose-6-Phosphate-Dehydrogenase (G6P...

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Veröffentlicht in:	PLoS neglected tropical diseases 2020-11, Vol.14 (11), p.e0008838
Hauptverfasser:	Thriemer, Kamala, Poespoprodjo, Jeanne-Rini, Kenangalem, Enny, Douglas, Nicholas M, Sugiarto, Paulus, Anstey, Nicholas M, Simpson, Julie Anne, Price, Ric N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Anaemia Anemia Antimalarials - adverse effects Antimalarials - therapeutic use Artemisinins - therapeutic use Biology and Life Sciences Body weight Child Child, Preschool Clinical outcomes Dihydroartemisinin Dosage Drug Administration Schedule Drug dosages Drug Therapy, Combination Ethics Ethnicity Female Glucosephosphate Dehydrogenase Deficiency - diagnosis Glucosephosphate Dehydrogenase Deficiency - epidemiology Health care Health care facilities Health services Human diseases Humans Indonesia - epidemiology Infant Infections Laboratories Malaria Malaria, Vivax - drug therapy Malaria, Vivax - epidemiology Male Medicine and Health Sciences Minority & ethnic groups Morbidity Mortality Outpatient care facilities Parasites Patients Pharmacy Plasmodium Plasmodium vivax - drug effects Primaquine Primaquine - adverse effects Primaquine - therapeutic use Records Retrospective Studies Surveying Tropical diseases Vector-borne diseases
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