Identification of intraductal carcinoma of the prostate on tissue specimens using Raman micro-spectroscopy: A diagnostic accuracy case-control study with multicohort validation

Author summaryWhy was this study done? Given its consistent association with prostate cancer (PC) recurrence, PC metastasis, and PC-specific death, the precise reporting of intraductal carcinoma of the prostate (IDC-P) is of the utmost importance. Pathologists nowadays rely mostly on morphology to d...

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Veröffentlicht in:	PLoS medicine 2020-08, Vol.17 (8), p.e1003281-e1003281, Article 1003281
Hauptverfasser:	Grosset, Andree-Anne, Dallaire, Frederick, Tien Nguyen, Birlea, Mirela, Wong, Jahg, Daoust, Francois, Roy, Noemi, Kougioumoutzakis, Andre, Azzi, Feryel, Aubertin, Kelly, Kadoury, Samuel, Latour, Mathieu, Albadine, Roula, Prendeville, Susan, Boutros, Paul, Fraser, Michael, Bristow, Rob G., van der Kwast, Theodorus, Orain, Michele, Brisson, Herve, Benzerdjeb, Nazim, Hovington, Helene, Bergeron, Alain, Fradet, Yves, Tetu, Bernard, Saad, Fred, Leblond, Frederic, Trudel, Dominique
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Algorithms Aluminum Biology and Life Sciences Biomarkers Canada - epidemiology Carcinoma, Intraductal, Noninfiltrating - diagnostic imaging Carcinoma, Intraductal, Noninfiltrating - epidemiology Carcinoma, Intraductal, Noninfiltrating - pathology Case-Control Studies Cohort Studies Computer and Information Sciences General & Internal Medicine Histopathology Humans Life Sciences & Biomedicine Light microscopy Light scattering Lipids Machine learning Machine Learning - standards Male Medicine and Health Sciences Medicine, General & Internal Microscopy Middle Aged Morphology Nonlinear Optical Microscopy - methods Nonlinear Optical Microscopy - standards Paraffin Pathology Patients People and Places Prostate Prostate cancer Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - epidemiology Prostatic Neoplasms - pathology Reproducibility of Results Retrospective Studies Ribonucleic acid RNA Science & Technology Slide preparation Spectroscopy Spectrum analysis Statistical analysis Support vector machines
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